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10.1371/journal.pone.0245518 http://scihub22266oqcxt.onion/10.1371/journal.pone.0245518 33444415!7808610!33444415     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2021 ; 16 (1): e0245518 Nephropedia Template TP {{tp|p=33444415|t=2021. High-risk chest radiographic features associated with COVID-19 disease severity |pdf=|usr=}}{{33444415}} gab.com Text High-risk chest radiographic features associated with COVID-19 disease severity JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=33444415 #FOAvip OBJECTIVES: High-risk CXR features in COVID-19 are not clearly defined. We aimed to identify CXR features that correlate with severe COVID-19. METHODS: All confirmed COVID-19 patients admitted within the study period were screened. Those with suboptimal baseline CXR were excluded. CXRs were reviewed by three independent radiologists and opacities recorded according to zones and laterality. The primary endpoint was defined as hypoxia requiring supplemental oxygen, and CXR features were assessed for association with this endpoint to identify high-risk features. These features were then used to define criteria for a high-risk CXR, and clinical features and outcomes of patients with and without baseline high-risk CXR were compared using logistic regression analysis. RESULTS: 109 patients were included. In the initial analysis of 40 patients (36.7%) with abnormal baseline CXR, presence of bilateral opacities, multifocal opacities, or any upper or middle zone opacity were associated with supplemental oxygen requirement. Of the entire cohort, 29 patients (26.6%) had a baseline CXR with at least one of these features. Having a high-risk baseline CXR was significantly associated with requiring supplemental oxygen in univariate (odds ratio 14.0, 95% confidence interval 3.90-55.60) and multivariate (adjusted odds ratio 8.38, 95% CI 2.43-28.97, P = 0.001) analyses. CONCLUSION: We identified several high-risk CXR features that are significantly associated with severe illness. The association of upper or middle zone opacities with severe illness has not been previously emphasized. Recognition of these specific high-risk CXR features is important to prioritize limited healthcare resources for sicker patients. Twit Text FOAVip High-risk chest radiographic features associated with COVID-19 disease severity ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=33444415 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33444415 #FOAvip English Wikipedia <ref>{{Cite pmid|33444415}}</ref> High-risk chest radiographic features associated with COVID-19 disease severity #MMPMID33444415 Ong SWX; Hui TCH; Lee YS; Haja Mohideen SM; Young BE; Tan CH; Lye DC PLoS One 2021[]; 16 (1): e0245518 PMID33444415show ga OBJECTIVES: High-risk CXR features in COVID-19 are not clearly defined. We aimed to identify CXR features that correlate with severe COVID-19. METHODS: All confirmed COVID-19 patients admitted within the study period were screened. Those with suboptimal baseline CXR were excluded. CXRs were reviewed by three independent radiologists and opacities recorded according to zones and laterality. The primary endpoint was defined as hypoxia requiring supplemental oxygen, and CXR features were assessed for association with this endpoint to identify high-risk features. These features were then used to define criteria for a high-risk CXR, and clinical features and outcomes of patients with and without baseline high-risk CXR were compared using logistic regression analysis. RESULTS: 109 patients were included. In the initial analysis of 40 patients (36.7%) with abnormal baseline CXR, presence of bilateral opacities, multifocal opacities, or any upper or middle zone opacity were associated with supplemental oxygen requirement. Of the entire cohort, 29 patients (26.6%) had a baseline CXR with at least one of these features. Having a high-risk baseline CXR was significantly associated with requiring supplemental oxygen in univariate (odds ratio 14.0, 95% confidence interval 3.90-55.60) and multivariate (adjusted odds ratio 8.38, 95% CI 2.43-28.97, P = 0.001) analyses. CONCLUSION: We identified several high-risk CXR features that are significantly associated with severe illness. The association of upper or middle zone opacities with severe illness has not been previously emphasized. Recognition of these specific high-risk CXR features is important to prioritize limited healthcare resources for sicker patients. |Adult[MESH] |COVID-19/*diagnostic imaging/pathology/virology[MESH] |Cohort Studies[MESH] |Emergency Service, Hospital[MESH] |Female[MESH] |Hospitalization[MESH] |Humans[MESH] |Lung/diagnostic imaging[MESH] |Male[MESH] |Middle Aged[MESH] |Radiography, Thoracic/methods[MESH] |Retrospective Studies[MESH] |Risk Factors[MESH] |SARS-CoV-2/isolation & purification[MESH] |Severity of Illness Index[MESH] |Thorax/diagnostic imaging[MESH]High-risk chest radiographic features associated with COVID-19 disease(epmc).pdf DeepDyve Pubget Overpricing