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33443334!ä!33443334

suck abstract from ncbi


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pmid33443334      Isr+Med+Assoc+J 2021 ; 23 (1): 7-10
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  • Convalescent Whole Blood Donors Screening Strategies for Providing Efficient and Safe COVID-19 Survivors Plasma and Other Blood Components #MMPMID33443334
  • Mandel M; Gurevich M; Mandelboim M; Amital H; Achiron A
  • Isr Med Assoc J 2021[Jan]; 23 (1): 7-10 PMID33443334show ga
  • BACKGROUND: During the coronavirus disease-2019 (COVID-19) pandemic outbreak our blood bank developed protocols to guarantee accurate blood components to COVID-19 patients. OBJECTIVES: To provide convalescent whole blood donor screening strategies for patients recovering from COVID-19. METHODS: We recruited COVID-19 recovering patients who met our defined inclusion criteria for whole blood donation. All blood units were screened for severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) RNA by real time reverse transcription polymerase chain reaction (RT-PCR) and SARS-COV-2 immunoglobulin G (IgG) antibodies against the S1 domain. RESULTS: We screened 180 blood units from patients recovering from COVID-19. All results were negative for SARS-CoV-2 RNA and 87.2% were positive for SARS-COV-2 IgG antibodies in the plasma. CONCLUSIONS: Blood component units from recovering COVID-19 patients are safe. Plasma units with positive IgG antibodies could serve as an efficient passive immunization for COVID-19 patients. Moreover, in the face of increased transfusion demand for treatment of anemia and coagulation dysfunction in critical ill COVID-19 patients, red blood cells units and random platelets units from convalescent donors can be safely transfused.
  • |*Blood Donors[MESH]
  • |*Donor Selection[MESH]
  • |Adult[MESH]
  • |Antibodies, Viral/immunology[MESH]
  • |COVID-19/*blood/immunology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunization, Passive/methods[MESH]
  • |Immunoglobulin G/blood[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |RNA, Viral/blood[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2/*immunology/isolation & purification[MESH]
  • |Survivors[MESH]


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