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10.7189/jogh.10.021104

http://scihub22266oqcxt.onion/10.7189/jogh.10.021104
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33437465!7774027!33437465
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suck abstract from ncbi

pmid33437465
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  • What is the evidence for transmission of COVID-19 by children in schools? A living systematic review #MMPMID33437465
  • Xu W; Li X; Dozier M; He Y; Kirolos A; Lang Z; Mathews C; Siegfried N; Theodoratou E
  • J Glob Health 2020[Dec]; 10 (2): 021104 PMID33437465show ga
  • Background: It is of paramount importance to understand the transmission of SARS-CoV-2 in schools, which could support the decision-making about educational facilities closure or re-opening with effective prevention and control measures in place. Methods: We conducted a systematic review and meta-analysis to investigate the extent of SARS-CoV-2 transmission in schools. We performed risk of bias evaluation of all included studies using the Newcastle-Ottawa Scale (NOS). Results: 2178 articles were retrieved and 11 studies were included. Five cohort studies reported a combined 22 student and 21 staff index cases that exposed 3345 contacts with 18 transmissions (overall infection attack rate (IAR): 0.08%, 95% confidence interval (CI) = 0.00%-0.86%). IARs for students and school staff were 0.15% (95% CI = 0.00%-0.93%) and 0.70% (95% CI = 0.00%-3.56%) respectively. Six cross-sectional studies reported 639 SARS-CoV-2 positive cases in 6682 study participants tested [overall SARS-CoV-2 positivity rate: 8.00% (95% CI = 2.17%-16.95%). SARS-CoV-2 positivity rate was estimated to be 8.74% (95% CI = 2.34%-18.53%) among students, compared to 13.68% (95% CI = 1.68%-33.89%) among school staff. Gender differences were not found for secondary infection (OR = 1.44, 95% CI = 0.50-4.14, P = 0.49) and SARS-CoV-2 positivity (OR = 0.90, 95% CI = 0.72-1.13, P = 0.36) in schools. Fever, cough, dyspnea, ageusia, anosmia, rhinitis, sore throat, headache, myalgia, asthenia, and diarrhoea were all associated with the detection of SARS-CoV-2 antibodies (based on two studies). Overall, study quality was judged to be poor with risk of performance and attrition bias, limiting the confidence in the results. Conclusions: There is limited high-quality evidence available to quantify the extent of SARS-CoV-2 transmission in schools or to compare it to community transmission. Emerging evidence suggests lower IAR and SARS-CoV-2 positivity rate in students compared to school staff. Future prospective and adequately controlled cohort studies are necessary to confirm this finding.
  • |*SARS-CoV-2[MESH]
  • |Adolescent[MESH]
  • |COVID-19/*transmission[MESH]
  • |Child[MESH]
  • |Cross-Sectional Studies[MESH]
  • |Disease Transmission, Infectious/*statistics & numerical data[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Schools/*statistics & numerical data[MESH]
  • |Students/*statistics & numerical data[MESH]


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  • suck abstract from ncbi

    021104 2.10 2020