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10.1097/JCMA.0000000000000485

http://scihub22266oqcxt.onion/10.1097/JCMA.0000000000000485
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33433137!ä!33433137

suck abstract from ncbi


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pmid33433137      J+Chin+Med+Assoc 2021 ; 84 (3): 245-247
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  • Pandemic aspect of dexamethasone: Molecular mechanisms and clinical application #MMPMID33433137
  • Li AFY; Wang CL; Tai HY; Fu YJ; Tsai FT; Tsai YC; Ko YL; Li MJ; Lin CC; Chang TJ
  • J Chin Med Assoc 2021[Mar]; 84 (3): 245-247 PMID33433137show ga
  • The rapid spread of coronavirus disease (COVID-19) in many countries has caused inconvenience in conducting daily life activities, and even deaths. Dexamethasone is a corticosteroid applied in clinical medicine since 1957, especially in immune therapy fields. Herein, we present the characteristics of Dexamethasone, from molecular mechanisms such as genomic and nongenomic pathways by cellular signal regulations, to clinical applications in various phases of the disease. During COVID-19 pandemic, Dexamethasone given to patients who required oxygen or ventilation therapy showed improved life efficacy.
  • |*COVID-19 Drug Treatment[MESH]
  • |*SARS-CoV-2[MESH]
  • |Dexamethasone/*pharmacology/therapeutic use[MESH]
  • |Humans[MESH]
  • |Receptors, Glucocorticoid/physiology[MESH]


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