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10.1136/bcr-2020-238413 http://scihub22266oqcxt.onion/10.1136/bcr-2020-238413 33431539!7802699!33431539     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMJ+Case+Rep 2021 ; 14 (1): ä Nephropedia Template TP {{tp|p=33431539|t=2021. Complete recovery from COVID-19 of a kidney-pancreas transplant recipient: potential benefit from everolimus?|pdf=|usr=}}{{33431539}} gab.com Text Complete recovery from COVID-19 of a kidney-pancreas transplant recipient: potential benefit from everolimus JO: BMJ Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=33431539 #FOAvip We present a kidney-pancreas transplant recipient who achieved complete recovery from COVID-19. A 45-year-old patient with T3 paraplegia underwent kidney-pancreas transplantation 18 years ago, followed by a subsequent kidney transplant 9 years ago, and presented with fever, hypoxia and hypotension after exposure to two confirmed cases of COVID-19. History of solid organ transplant, pre-existing renal impairment, asthma and an elevated D-dimer were identified as established risk factors for severe COVID-19. Supportive management was provided, baseline immunosuppression with everolimus was continued, and oral prednisolone was increased. A complete recovery was observed. Given the favourable outcome despite risk factors for severe COVID-19, we identify and review the potential mitigating roles of immunosuppression and mammalian target of rapamycin (mTOR) inhibitors in this disease. Further investigation is required to establish whether mTOR inhibitors could be used as therapeutic agents to treat COVID-19, or as alternative immunosuppression implemented early in the COVID-19 disease course. Twit Text FOAVip Complete recovery from COVID-19 of a kidney-pancreas transplant recipient: potential benefit from everolimus ????BMJ Case Rep http://www.kidney.de/pget.php?&tw=1&pmid=33431539 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33431539 #FOAvip English Wikipedia <ref>{{Cite pmid|33431539}}</ref> Complete recovery from COVID-19 of a kidney-pancreas transplant recipient: potential benefit from everolimus? #MMPMID33431539 Heron VC; Bach CT; Holmes NE; Whitlam JB BMJ Case Rep 2021[Jan]; 14 (1): ä PMID33431539show ga We present a kidney-pancreas transplant recipient who achieved complete recovery from COVID-19. A 45-year-old patient with T3 paraplegia underwent kidney-pancreas transplantation 18 years ago, followed by a subsequent kidney transplant 9 years ago, and presented with fever, hypoxia and hypotension after exposure to two confirmed cases of COVID-19. History of solid organ transplant, pre-existing renal impairment, asthma and an elevated D-dimer were identified as established risk factors for severe COVID-19. Supportive management was provided, baseline immunosuppression with everolimus was continued, and oral prednisolone was increased. A complete recovery was observed. Given the favourable outcome despite risk factors for severe COVID-19, we identify and review the potential mitigating roles of immunosuppression and mammalian target of rapamycin (mTOR) inhibitors in this disease. Further investigation is required to establish whether mTOR inhibitors could be used as therapeutic agents to treat COVID-19, or as alternative immunosuppression implemented early in the COVID-19 disease course. |*Kidney Transplantation[MESH] |*Pancreas Transplantation[MESH] |Accidents, Traffic[MESH] |Asthma/complications[MESH] |COVID-19/*complications/metabolism/physiopathology/therapy[MESH] |Diabetes Mellitus, Type 1/complications/surgery[MESH] |Everolimus/therapeutic use[MESH] |Fever/physiopathology[MESH] |Fibrin Fibrinogen Degradation Products/metabolism[MESH] |Glucocorticoids/*therapeutic use[MESH] |Graft Rejection/*prevention & control[MESH] |Humans[MESH] |Hypotension/physiopathology[MESH] |Hypoxia/physiopathology[MESH] |Immunosuppressive Agents/*therapeutic use[MESH] |Male[MESH] |Middle Aged[MESH] |Paraplegia/*complications[MESH] |Prednisolone/therapeutic use[MESH] |SARS-CoV-2[MESH]Complete recovery from COVID-19 of a kidney-pancreas transplant recipi(epmc).pdf DeepDyve Pubget Overpricing