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suck abstract from ncbi


10.3390/ijerph18020408

http://scihub22266oqcxt.onion/10.3390/ijerph18020408
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33430189!7825589!33430189
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suck abstract from ncbi


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pmid33430189      Int+J+Environ+Res+Public+Health 2021 ; 18 (2): ä
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  • Recruitment and Baseline Characteristics of Participants in the AgeWell de Study-A Pragmatic Cluster-Randomized Controlled Lifestyle Trial against Cognitive Decline #MMPMID33430189
  • Rohr S; Zulke A; Luppa M; Brettschneider C; Weissenborn M; Kuhne F; Zollinger I; Samos FZ; Bauer A; Dohring J; Krebs-Hein K; Oey A; Czock D; Frese T; Gensichen J; Haefeli WE; Hoffmann W; Kaduszkiewicz H; Konig HH; Thyrian JR; Wiese B; Riedel-Heller SG
  • Int J Environ Res Public Health 2021[Jan]; 18 (2): ä PMID33430189show ga
  • Targeting dementia prevention, first trials addressing multiple modifiable risk factors showed promising results in at-risk populations. In Germany, AgeWell.de is the first large-scale initiative investigating the effectiveness of a multi-component lifestyle intervention against cognitive decline. We aimed to investigate the recruitment process and baseline characteristics of the AgeWell.de participants to gain an understanding of the at-risk population and who engages in the intervention. General practitioners across five study sites recruited participants (aged 60-77 years, Cardiovascular Risk Factors, Aging, and Incidence of Dementia/CAIDE dementia risk score >/= 9). Structured face-to-face interviews were conducted with eligible participants, including neuropsychological assessments. We analyzed group differences between (1) eligible vs. non-eligible participants, (2) participants vs. non-participants, and (3) between intervention groups. Of 1176 eligible participants, 146 (12.5%) dropped out before baseline; the study population was thus 1030 individuals. Non-participants did not differ from participants in key sociodemographic factors and dementia risk. Study participants were M = 69.0 (SD = 4.9) years old, and 52.1% were women. The average Montreal Cognitive Assessment/MoCA score was 24.5 (SD = 3.1), indicating a rather mildly cognitively impaired study population; however, 39.4% scored >/= 26, thus being cognitively unimpaired. The bandwidth of cognitive states bears the interesting potential for differential trial outcome analyses. However, trial conduction is impacted by the COVID-19 pandemic, requiring adjustments to the study protocol with yet unclear methodological consequences.
  • |*Life Style[MESH]
  • |*Patient Selection[MESH]
  • |Aged[MESH]
  • |Cognitive Dysfunction/*prevention & control[MESH]
  • |Female[MESH]
  • |Germany[MESH]
  • |Healthy Aging[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]


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