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10.5055/jom.2020.0597 http://scihub22266oqcxt.onion/10.5055/jom.2020.0597 33428186!8011291!33428186     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Opioid+Manag 2020 ; 16 (6): 401-404 Nephropedia Template TP {{tp|p=33428186|t=2020. The impact of long-term opioid use on the risk and severity of COVID-19 |pdf=|usr=}}{{33428186}} gab.com Text The impact of long-term opioid use on the risk and severity of COVID-19 JO: J Opioid Manag http://www.kidney.de/pget.php?&tw=1&pmid=33428186 #FOAvip Based on evidence of the immunosuppressive effects of chronic opioids, long-term users of prescription and illicit opioids comprise an unrecognized but growing population of Americans with compromised immune function and respiratory depression who may be at high risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19)-related hospitalization, prolonged ICU stay, adverse events, and death. This perspective is of broad clinical and public health importance because the US has the highest population of long-term users of prescription opioids, a sequel of a decade-long practice of opioid overprescribing in the US. For long-term opioid users who are hospitalized for COVID-19, clinicians face clinical challenges arising from the suppressive effects of opioids on the respiratory and immune functions, as well as the potential for adverse drug-drug interaction when opioids have to be continued in long-term users. More research is needed to further understand the association of long-term opioid use and susceptibility to COVID-19 and other emerging infections. Twit Text FOAVip The impact of long-term opioid use on the risk and severity of COVID-19 ????J Opioid Manag http://www.kidney.de/pget.php?&tw=1&pmid=33428186 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33428186 #FOAvip English Wikipedia <ref>{{Cite pmid|33428186}}</ref> The impact of long-term opioid use on the risk and severity of COVID-19 #MMPMID33428186 Shah R; Kuo YF; Baillargeon J; Raji MA J Opioid Manag 2020[Nov]; 16 (6): 401-404 PMID33428186show ga Based on evidence of the immunosuppressive effects of chronic opioids, long-term users of prescription and illicit opioids comprise an unrecognized but growing population of Americans with compromised immune function and respiratory depression who may be at high risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease 19 (COVID-19)-related hospitalization, prolonged ICU stay, adverse events, and death. This perspective is of broad clinical and public health importance because the US has the highest population of long-term users of prescription opioids, a sequel of a decade-long practice of opioid overprescribing in the US. For long-term opioid users who are hospitalized for COVID-19, clinicians face clinical challenges arising from the suppressive effects of opioids on the respiratory and immune functions, as well as the potential for adverse drug-drug interaction when opioids have to be continued in long-term users. More research is needed to further understand the association of long-term opioid use and susceptibility to COVID-19 and other emerging infections. |Analgesics, Opioid/*adverse effects[MESH] |COVID-19/*complications[MESH] |Humans[MESH] |Immunocompromised Host[MESH] |Opioid-Related Disorders/*complications[MESH] |Respiratory Insufficiency[MESH]The impact of long-term opioid use on the risk and severity of COVID-1(epmc).pdf DeepDyve Pubget Overpricing