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10.1007/s41061-020-00318-2

http://scihub22266oqcxt.onion/10.1007/s41061-020-00318-2
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33428032!7797499!33428032
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suck abstract from ncbi


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pmid33428032      Top+Curr+Chem+(Cham) 2021 ; 379 (1): 4
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  • Reviews on Biological Activity, Clinical Trial and Synthesis Progress of Small Molecules for the Treatment of COVID-19 #MMPMID33428032
  • Li D; Hu J; Li D; Yang W; Yin SF; Qiu R
  • Top Curr Chem (Cham) 2021[Jan]; 379 (1): 4 PMID33428032show ga
  • COVID-19 has broken out rapidly in nearly all countries worldwide, and has blossomed into a pandemic. Since the beginning of the spread of COVID-19, many scientists have been cooperating to study a vast array of old drugs and new clinical trial drugs to discover potent drugs with anti-COVID-19 activity, including antiviral drugs, antimalarial drugs, immunosuppressants, Chinese medicines, M(pro) inhibitors, JAK inhibitors, etc. The most commonly used drugs are antiviral compounds, antimalarial drugs and JAK inhibitors. In this review, we summarize mainly the antimalarial drugs chloroquine and hydroxychloroquine, the antiviral drugs Favipiravir and Remdesivir, and JAK inhibitor Ruxolitinib, discussing their biological activities, clinical trials and synthesis progress.
  • |*COVID-19 Drug Treatment[MESH]
  • |*Small Molecule Libraries[MESH]
  • |Antimalarials/therapeutic use[MESH]
  • |Antiviral Agents/*chemical synthesis/*pharmacology/therapeutic use[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Drug Repositioning[MESH]
  • |Humans[MESH]


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