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10.3389/fped.2020.626182

http://scihub22266oqcxt.onion/10.3389/fped.2020.626182
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33425823!7793714!33425823
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suck abstract from ncbi


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pmid33425823      Front+Pediatr 2020 ; 8 (ä): 626182
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  • Multisystem Inflammatory Syndrome in Children (MIS-C), a Post-viral Myocarditis and Systemic Vasculitis-A Critical Review of Its Pathogenesis and Treatment #MMPMID33425823
  • McMurray JC; May JW; Cunningham MW; Jones OY
  • Front Pediatr 2020[]; 8 (ä): 626182 PMID33425823show ga
  • MIS-C is a newly defined post-viral myocarditis and inflammatory vasculopathy of children following COVID-19 infection. This review summarizes the literature on diagnosis, parameters of disease severity, and current treatment regimens. The clinical perspective was analyzed in light of potential immunopathogenesis and compared to other post-infectious and inflammatory illnesses of children affecting the heart. In this paradigm, the evidence supports the importance of endothelial injury and activation of the IL-1 pathway as a common determinant among MIS-C, Kawasaki disease, and Acute Rheumatic fever.
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