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10.1007/s40820-020-00565-4

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suck abstract from ncbi


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pmid33425476      Nanomicro+Lett 2021 ; 13 (ä): 52
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  • Charge-Transfer Resonance and Electromagnetic Enhancement Synergistically Enabling MXenes with Excellent SERS Sensitivity for SARS-CoV-2 S Protein Detection #MMPMID33425476
  • Peng Y; Lin C; Long L; Masaki T; Tang M; Yang L; Liu J; Huang Z; Li Z; Luo X; Lombardi JR; Yang Y
  • Nanomicro Lett 2021[Jan]; 13 (ä): 52 PMID33425476show ga
  • The outbreak of coronavirus disease 2019 has seriously threatened human health. Rapidly and sensitively detecting SARS-CoV-2 viruses can help control the spread of viruses. However, it is an arduous challenge to apply semiconductor-based substrates for virus SERS detection due to their poor sensitivity. Therefore, it is worthwhile to search novel semiconductor-based substrates with excellent SERS sensitivity. Herein we report, for the first time, Nb(2)C and Ta(2)C MXenes exhibit a remarkable SERS enhancement, which is synergistically enabled by the charge transfer resonance enhancement and electromagnetic enhancement. Their SERS sensitivity is optimized to 3.0 x 10(6) and 1.4 x 10(6) under the optimal resonance excitation wavelength of 532 nm. Additionally, remarkable SERS sensitivity endows Ta(2)C MXenes with capability to sensitively detect and accurately identify the SARS-CoV-2 spike protein. Moreover, its detection limit is as low as 5 x 10(-9) M, which is beneficial to achieve real-time monitoring and early warning of novel coronavirus. This research not only provides helpful theoretical guidance for exploring other novel SERS-active semiconductor-based materials but also provides a potential candidate for the practical applications of SERS technology.
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