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10.1016/j.addr.2021.01.003 http://scihub22266oqcxt.onion/10.1016/j.addr.2021.01.003 33422546!7789827!33422546     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Adv+Drug+Deliv+Rev 2021 ; 170 (ä): 113-141 Nephropedia Template TP {{tp|p=33422546|t=2021. Advances in gene-based vaccine platforms to address the COVID-19 pandemic |pdf=|usr=}}{{33422546}} gab.com Text Advances in gene-based vaccine platforms to address the COVID-19 pandemic JO: Adv Drug Deliv Rev http://www.kidney.de/pget.php?&tw=1&pmid=33422546 #FOAvip The novel betacoronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has spread across the globe at an unprecedented rate since its first emergence in Wuhan City, China in December 2019. Scientific communities around the world have been rigorously working to develop a potent vaccine to combat COVID-19 (coronavirus disease 2019), employing conventional and novel vaccine strategies. Gene-based vaccine platforms based on viral vectors, DNA, and RNA, have shown promising results encompassing both humoral and cell-mediated immune responses in previous studies, supporting their implementation for COVID-19 vaccine development. In fact, the U.S. Food and Drug Administration (FDA) recently authorized the emergency use of two RNA-based COVID-19 vaccines. We review current gene-based vaccine candidates proceeding through clinical trials, including their antigenic targets, delivery vehicles, and route of administration. Important features of previous gene-based vaccine developments against other infectious diseases are discussed in guiding the design and development of effective vaccines against COVID-19 and future derivatives. Twit Text FOAVip Advances in gene-based vaccine platforms to address the COVID-19 pandemic ????Adv Drug Deliv Rev http://www.kidney.de/pget.php?&tw=1&pmid=33422546 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33422546 #FOAvip English Wikipedia <ref>{{Cite pmid|33422546}}</ref> Advances in gene-based vaccine platforms to address the COVID-19 pandemic #MMPMID33422546 Pushparajah D; Jimenez S; Wong S; Alattas H; Nafissi N; Slavcev RA Adv Drug Deliv Rev 2021[Mar]; 170 (ä): 113-141 PMID33422546show ga The novel betacoronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has spread across the globe at an unprecedented rate since its first emergence in Wuhan City, China in December 2019. Scientific communities around the world have been rigorously working to develop a potent vaccine to combat COVID-19 (coronavirus disease 2019), employing conventional and novel vaccine strategies. Gene-based vaccine platforms based on viral vectors, DNA, and RNA, have shown promising results encompassing both humoral and cell-mediated immune responses in previous studies, supporting their implementation for COVID-19 vaccine development. In fact, the U.S. Food and Drug Administration (FDA) recently authorized the emergency use of two RNA-based COVID-19 vaccines. We review current gene-based vaccine candidates proceeding through clinical trials, including their antigenic targets, delivery vehicles, and route of administration. Important features of previous gene-based vaccine developments against other infectious diseases are discussed in guiding the design and development of effective vaccines against COVID-19 and future derivatives. |Animals[MESH] |COVID-19 Vaccines/*administration & dosage/genetics/immunology[MESH] |COVID-19/epidemiology/genetics/immunology/*prevention & control[MESH] |Clinical Trials as Topic/methods[MESH] |Humans[MESH] |Pandemics/*prevention & control[MESH] |SARS-CoV-2/*drug effects/genetics/immunology[MESH] |Vaccines, Synthetic/*administration & dosage/genetics/immunology[MESH] |Viral Vaccines/*administration & dosage/genetics/immunology[MESH]Advances in gene-based vaccine platforms to address the COVID-19 pande(epmc).pdf DeepDyve Pubget Overpricing