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10.1002/prp2.705

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33421347!7796804!33421347
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suck abstract from ncbi


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pmid33421347      Pharmacol+Res+Perspect 2021 ; 9 (1): e00705
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  • Drug-drug interactions with candidate medications used for COVID-19 treatment: An overview #MMPMID33421347
  • Rezaee H; Pourkarim F; Pourtaghi-Anvarian S; Entezari-Maleki T; Asvadi-Kermani T; Nouri-Vaskeh M
  • Pharmacol Res Perspect 2021[Feb]; 9 (1): e00705 PMID33421347show ga
  • Drug-drug interaction (DDI) is a common clinical problem that has occurred as a result of the concomitant use of multiple drugs. DDI may occur in patients under treatment with medications used for coronavirus disease 2019 (COVID-19; i.e., chloroquine, lopinavir/ritonavir, ribavirin, tocilizumab, and remdesivir) and increase the risk of serious adverse reactions such as QT-prolongation, retinopathy, increased risk of infection, and hepatotoxicity. This review focuses on summarizing DDIs for candidate medications used for COVID-19 in order to minimize the adverse reactions.
  • |*COVID-19 Drug Treatment[MESH]
  • |*SARS-CoV-2[MESH]
  • |Animals[MESH]
  • |Antibodies, Monoclonal, Humanized/therapeutic use[MESH]
  • |Antiviral Agents/*therapeutic use[MESH]
  • |Chloroquine/therapeutic use[MESH]
  • |Drug Interactions[MESH]
  • |Humans[MESH]
  • |Lopinavir/therapeutic use[MESH]
  • |Ribavirin/therapeutic use[MESH]


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