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10.1016/j.jtcvs.2020.11.073

http://scihub22266oqcxt.onion/10.1016/j.jtcvs.2020.11.073
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33419553!7704331!33419553
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suck abstract from ncbi


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pmid33419553      J+Thorac+Cardiovasc+Surg 2022 ; 163 (3): 1071-1079.e3
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  • Venovenous extracorporeal membrane oxygenation for patients with refractory coronavirus disease 2019 (COVID-19): Multicenter experience of referral hospitals in a large health care system #MMPMID33419553
  • Shih E; DiMaio JM; Squiers JJ; Banwait JK; Meyer DM; George TJ; Schwartz GS
  • J Thorac Cardiovasc Surg 2022[Mar]; 163 (3): 1071-1079.e3 PMID33419553show ga
  • BACKGROUND: The benefit of extracorporeal membrane oxygenation (ECMO) for patients with severe acute respiratory distress from coronavirus disease 2019 refractory to medical management and lung-protective mechanical ventilation has not been adequately determined. METHODS: We reviewed the clinical course of 37 patients with laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection supported by venovenous ECMO at 4 ECMO referral centers within a large health care system. Patient characteristics, progression of hemodynamics and inflammatory markers, and clinical outcomes were evaluated. RESULTS: The patients had median age of 51 years (interquartile range, 40-59), and 73% were male. Peak plateau pressures, vasopressor requirements, and arterial partial pressure of carbon dioxide all improved with ECMO support. In our patient population, 24 of 37 patients (64.8%) survived to decannulation and 21 of 37 patients (56.8%) survived to discharge. Among patients discharged alive from the ECMO facility, 12 patients were discharged to a long-term acute care or rehabilitation facility, 2 were transferred back to the referring hospital for ventilatory weaning, and 7 were discharged directly home. For patients who were successfully decannulated, median length of time on ECMO was 17 days (interquartile range, 10-33.5). CONCLUSIONS: Venovenous ECMO represents a useful therapy for patients with refractory severe acute respiratory distress syndrome from coronavirus disease 2019.
  • |*Extracorporeal Membrane Oxygenation[MESH]
  • |Adult[MESH]
  • |Aged[MESH]
  • |COVID-19/mortality/*therapy[MESH]
  • |Disease Progression[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Patient Acuity[MESH]
  • |Retrospective Studies[MESH]
  • |Secondary Care Centers[MESH]
  • |Survival Analysis[MESH]
  • |Tertiary Care Centers[MESH]


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