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10.1007/s00210-020-02034-6 http://scihub22266oqcxt.onion/10.1007/s00210-020-02034-6 33416933!7792551!33416933     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Naunyn+Schmiedebergs+Arch+Pharmacol 2021 ; 394 (5): 997-1001 Nephropedia Template TP {{tp|p=33416933|t=2021. Chloroquine/hydroxychloroquine: an inflammasome inhibitor in severe COVID-19?|pdf=|usr=}}{{33416933}} gab.com Text Chloroquine/hydroxychloroquine: an inflammasome inhibitor in severe COVID-19 JO: Naunyn Schmiedebergs Arch Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33416933 #FOAvip Chloroquine and hydroxychloroquine belong to the aminoquinoline drugs. Studies revealed that chloroquine and hydroxychloroquine shows antagonism activity against COVID-19 under laboratory conditions. ARDS and ALI are conditions that occur in patients with COVID-19 as the main pathological complications of cytokine storm. Inflammasomes play a key role in the pathogenesis of many diseases associated with destructive inflammation. NLRP3 inflammasome has been shown to play a key role in the pathogenesis of viral diseases. The possible role of NLRP3 inflammasome inhibitors in the treatment of COVID-19 has been considered. We surveyed the potential inhibitory effect of chloroquine and hydroxychloroquine on inflammasome. Studies indicate that one of the possible anti-inflammatory mechanisms of chloroquine and hydroxychloroquine is inhibition of the activity of NLRP3 inflammasome. Twit Text FOAVip Chloroquine/hydroxychloroquine: an inflammasome inhibitor in severe COVID-19 ????Naunyn Schmiedebergs Arch Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=33416933 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33416933 #FOAvip English Wikipedia <ref>{{Cite pmid|33416933}}</ref> Chloroquine/hydroxychloroquine: an inflammasome inhibitor in severe COVID-19? #MMPMID33416933 Bahadoram M; Keikhaei B; Saeedi-Boroujeni A; Mahmoudian-Sani MR Naunyn Schmiedebergs Arch Pharmacol 2021[May]; 394 (5): 997-1001 PMID33416933show ga Chloroquine and hydroxychloroquine belong to the aminoquinoline drugs. Studies revealed that chloroquine and hydroxychloroquine shows antagonism activity against COVID-19 under laboratory conditions. ARDS and ALI are conditions that occur in patients with COVID-19 as the main pathological complications of cytokine storm. Inflammasomes play a key role in the pathogenesis of many diseases associated with destructive inflammation. NLRP3 inflammasome has been shown to play a key role in the pathogenesis of viral diseases. The possible role of NLRP3 inflammasome inhibitors in the treatment of COVID-19 has been considered. We surveyed the potential inhibitory effect of chloroquine and hydroxychloroquine on inflammasome. Studies indicate that one of the possible anti-inflammatory mechanisms of chloroquine and hydroxychloroquine is inhibition of the activity of NLRP3 inflammasome. |*COVID-19 Drug Treatment[MESH] |Anti-Inflammatory Agents/*therapeutic use[MESH] |Chloroquine/*therapeutic use[MESH] |Cytokine Release Syndrome[MESH] |Humans[MESH] |Hydroxychloroquine/*therapeutic use[MESH] |Inflammasomes/*drug effects[MESH]Chloroquine/hydroxychloroquine: an inflammasome inhibitor in severe CO(epmc).pdf DeepDyve Pubget Overpricing