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10.1080/22221751.2021.1872352 http://scihub22266oqcxt.onion/10.1080/22221751.2021.1872352 33407005!7832474!33407005     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Emerg+Microbes+Infect 2021 ; 10 (1): 152-160 Nephropedia Template TP {{tp|p=33407005|t=2021. Critical role of neutralizing antibody for SARS-CoV-2 reinfection and transmission |pdf=|usr=}}{{33407005}} gab.com Text Critical role of neutralizing antibody for SARS-CoV-2 reinfection and transmission JO: Emerg Microbes Infect http://www.kidney.de/pget.php?&tw=1&pmid=33407005 #FOAvip Cases of laboratory-confirmed SARS-CoV-2 reinfection have been reported in a number of countries. Further, the level of natural immunity induced by SARS-CoV-2 infection is not fully clear, nor is it clear if a primary infection is protective against reinfection. To investigate the potential association between serum antibody titres and reinfection of SARS-CoV-2, ferrets with different levels of NAb titres after primary SARS-CoV-2 infection were subjected to reinfection with a heterologous SARS-CoV-2 strain. All heterologous SARS-CoV-2 reinfected ferrets showed active virus replication in the upper respiratory and gastro-intestinal tracts. However, the high NAb titre group showed attenuated viral replication and rapid viral clearance. In addition, direct-contact transmission was observed only from reinfected ferrets with low NAb titres (<20), and not from other groups. Further, lung histopathology demonstrated the presence of limited inflammatory regions in the high NAb titre groups compared with control and low NAb groups. This study demonstrates a close correlation between a low NAb titre and SARS-CoV-2 reinfection in a recovered ferret reinfection model. Twit Text FOAVip Critical role of neutralizing antibody for SARS-CoV-2 reinfection and transmission ????Emerg Microbes Infect http://www.kidney.de/pget.php?&tw=1&pmid=33407005 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33407005 #FOAvip English Wikipedia <ref>{{Cite pmid|33407005}}</ref> Critical role of neutralizing antibody for SARS-CoV-2 reinfection and transmission #MMPMID33407005 Kim YI; Kim SM; Park SJ; Kim EH; Yu KM; Chang JH; Kim EJ; Casel MAB; Rollon R; Jang SG; Um J; Song MS; Jeong HW; Kim EG; Kim Y; Kim SY; Park JS; Park MS; Kwon GY; Yeo SG; Lee SA; Choi YJ; Jung JU; Choi YK Emerg Microbes Infect 2021[Dec]; 10 (1): 152-160 PMID33407005show ga Cases of laboratory-confirmed SARS-CoV-2 reinfection have been reported in a number of countries. Further, the level of natural immunity induced by SARS-CoV-2 infection is not fully clear, nor is it clear if a primary infection is protective against reinfection. To investigate the potential association between serum antibody titres and reinfection of SARS-CoV-2, ferrets with different levels of NAb titres after primary SARS-CoV-2 infection were subjected to reinfection with a heterologous SARS-CoV-2 strain. All heterologous SARS-CoV-2 reinfected ferrets showed active virus replication in the upper respiratory and gastro-intestinal tracts. However, the high NAb titre group showed attenuated viral replication and rapid viral clearance. In addition, direct-contact transmission was observed only from reinfected ferrets with low NAb titres (<20), and not from other groups. Further, lung histopathology demonstrated the presence of limited inflammatory regions in the high NAb titre groups compared with control and low NAb groups. This study demonstrates a close correlation between a low NAb titre and SARS-CoV-2 reinfection in a recovered ferret reinfection model. |Animals[MESH] |Antibodies, Neutralizing/*blood[MESH] |Antibodies, Viral/*blood[MESH] |COVID-19/*immunology/*transmission/virology[MESH] |Chlorocebus aethiops[MESH] |Ferrets[MESH] |Reinfection/*immunology[MESH] |SARS-CoV-2/*immunology[MESH]Critical role of neutralizing antibody for SARS-CoV-2 reinfection and (epmc).pdf DeepDyve Pubget Overpricing