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10.1080/22221751.2021.1872353 http://scihub22266oqcxt.onion/10.1080/22221751.2021.1872353 33399028!7872537!33399028     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Emerg+Microbes+Infect 2021 ; 10 (1): 196-205 Nephropedia Template TP {{tp|p=33399028|t=2021. The interplay between emerging human coronavirus infections and autophagy |pdf=|usr=}}{{33399028}} gab.com Text The interplay between emerging human coronavirus infections and autophagy JO: Emerg Microbes Infect http://www.kidney.de/pget.php?&tw=1&pmid=33399028 #FOAvip ABSTRACT Following outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) in 2002 and 2012, respectively, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the third highly pathogenic emerging human coronavirus (hCoV). SARS-CoV-2 is currently causing the global coronavirus disease 2019 (COVID-19) pandemic. CoV infections in target cells may stimulate the formation of numerous double-membrane autophagosomes and induce autophagy. Several studies provided evidence that hCoV infections are closely related to various cellular aspects associated with autophagy. Autophagy may even promote hCoV infection and replication. However, so far it is unclear how hCoV infections induce autophagy and whether the autophagic machinery is necessary for viral propagation. Here, we summarize the most recent advances concerning the mutual interplay between the autophagic machinery and the three emerging hCoVs, SARS-CoV, MERS-CoV, and SARS-CoV-2 and the model system mouse hepatitis virus. We also discuss the applicability of approved and well-tolerated drugs targeting autophagy as a potential treatment against COVID-19. Twit Text FOAVip The interplay between emerging human coronavirus infections and autophagy ????Emerg Microbes Infect http://www.kidney.de/pget.php?&tw=1&pmid=33399028 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33399028 #FOAvip English Wikipedia <ref>{{Cite pmid|33399028}}</ref> The interplay between emerging human coronavirus infections and autophagy #MMPMID33399028 Zhao Z; Lu K; Mao B; Liu S; Trilling M; Huang A; Lu M; Lin Y Emerg Microbes Infect 2021[Dec]; 10 (1): 196-205 PMID33399028show ga ABSTRACT Following outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV) in 2002 and 2012, respectively, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the third highly pathogenic emerging human coronavirus (hCoV). SARS-CoV-2 is currently causing the global coronavirus disease 2019 (COVID-19) pandemic. CoV infections in target cells may stimulate the formation of numerous double-membrane autophagosomes and induce autophagy. Several studies provided evidence that hCoV infections are closely related to various cellular aspects associated with autophagy. Autophagy may even promote hCoV infection and replication. However, so far it is unclear how hCoV infections induce autophagy and whether the autophagic machinery is necessary for viral propagation. Here, we summarize the most recent advances concerning the mutual interplay between the autophagic machinery and the three emerging hCoVs, SARS-CoV, MERS-CoV, and SARS-CoV-2 and the model system mouse hepatitis virus. We also discuss the applicability of approved and well-tolerated drugs targeting autophagy as a potential treatment against COVID-19. |*Autophagy[MESH] |Animals[MESH] |Autophagosomes/*virology[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19/*physiopathology[MESH] |Clinical Trials as Topic[MESH] |Genome, Viral[MESH] |Humans[MESH] |Mice[MESH] |Middle East Respiratory Syndrome Coronavirus/genetics/pathogenicity[MESH] |Murine hepatitis virus/pathogenicity[MESH] |SARS-CoV-2/genetics/*pathogenicity[MESH] |Severe acute respiratory syndrome-related coronavirus/genetics/pathogenicity[MESH]The interplay between emerging human coronavirus infections and autoph(epmc).pdf DeepDyve Pubget Overpricing