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10.1007/s12272-020-01301-7 http://scihub22266oqcxt.onion/10.1007/s12272-020-01301-7 33398692!7781412!33398692     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Arch+Pharm+Res 2021 ; 44 (1): 99-116 Nephropedia Template TP {{tp|p=33398692|t=2021. Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective |pdf=|usr=}}{{33398692}} gab.com Text Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective JO: Arch Pharm Res http://www.kidney.de/pget.php?&tw=1&pmid=33398692 #FOAvip The novel beta coronavirus (SARS-CoV-2, designated as COVID-19) that is responsible for severe acute respiratory syndrome has devastated the global economy and health care system. Since COVID-19 changed the definition of "normal" in ordinary life around the world, the development of effective therapeutics and preventive measures is desperately needed to fight SARS-CoV-2 infection and restore normalcy. A clear understanding of COVID-19 pathogenesis is crucial in providing the scientific rationale necessary to develop anti-COVID19 drugs and vaccines. According to the most recently published literature, COVID-19 pathogenesis was postulated to occur in three sequential phases: pulmonary, proinflammatory, and prothrombic. Herein, virus-host interactions, potential pathogenic mechanisms, and clinical manifestations are described for each phase. Additionally, based on this pathogenesis model, various therapeutic strategies involving current clinical trials are presented with an explanation of their modes of action and example drugs. This review is a thorough, updated summary of COVID-19 pathogenesis and the therapeutic options available for this disease. Twit Text FOAVip Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective ????Arch Pharm Res http://www.kidney.de/pget.php?&tw=1&pmid=33398692 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33398692 #FOAvip English Wikipedia <ref>{{Cite pmid|33398692}}</ref> Overview of COVID-19 inflammatory pathogenesis from the therapeutic perspective #MMPMID33398692 Lee C; Choi WJ Arch Pharm Res 2021[Jan]; 44 (1): 99-116 PMID33398692show ga The novel beta coronavirus (SARS-CoV-2, designated as COVID-19) that is responsible for severe acute respiratory syndrome has devastated the global economy and health care system. Since COVID-19 changed the definition of "normal" in ordinary life around the world, the development of effective therapeutics and preventive measures is desperately needed to fight SARS-CoV-2 infection and restore normalcy. A clear understanding of COVID-19 pathogenesis is crucial in providing the scientific rationale necessary to develop anti-COVID19 drugs and vaccines. According to the most recently published literature, COVID-19 pathogenesis was postulated to occur in three sequential phases: pulmonary, proinflammatory, and prothrombic. Herein, virus-host interactions, potential pathogenic mechanisms, and clinical manifestations are described for each phase. Additionally, based on this pathogenesis model, various therapeutic strategies involving current clinical trials are presented with an explanation of their modes of action and example drugs. This review is a thorough, updated summary of COVID-19 pathogenesis and the therapeutic options available for this disease. |*COVID-19 Drug Treatment[MESH] |Angiotensin-Converting Enzyme 2/*metabolism[MESH] |Animals[MESH] |Antiviral Agents/administration & dosage/metabolism[MESH] |COVID-19/immunology/*metabolism[MESH] |Cytokine Release Syndrome/drug therapy/immunology/metabolism[MESH] |Humans[MESH] |Immunity, Innate/*drug effects/physiology[MESH]Overview of COVID-19 inflammatory pathogenesis from the therapeutic pe(epmc).pdf DeepDyve Pubget Overpricing