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10.1017/S0950268820003179

http://scihub22266oqcxt.onion/10.1017/S0950268820003179
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33397542!8245341!33397542
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suck abstract from ncbi


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pmid33397542      Epidemiol+Infect 2021 ; 149 (ä): e144
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  • Obesity is associated with severe COVID-19 but not death: a dose-response meta-analysis #MMPMID33397542
  • Deng L; Zhang J; Wang M; Chen L
  • Epidemiol Infect 2021[Jan]; 149 (ä): e144 PMID33397542show ga
  • The coronavirus disease 2019 (COVID-19) epidemic is spreading globally. Studies revealed that obesity may affect the progression and prognosis of COVID-19 patients. The aim of the meta-analysis is to identify the prevalence and impact of obesity on COVID-19. Studies on obese COVID-19 patients were obtained by searching PubMed, Cochrane Library databases and Web of Science databases, up to date to 5 June 2020. And the prevalence rate and the odds ratio (OR) of obesity with 95% confidence interval (CI) were used as comprehensive indicators for analysis using a random-effects model. A total of 6081 patients in 11 studies were included. The prevalence of obesity in patients with COVID-19 was 30% (95% CI 21-39%). Obese patients were 1.79 times more likely to develop severe COVID-19 than non-obese patients (OR 1.79, 95% CI 1.52-2.11, P < 0.0001, I2 = 0%). However obesity was not associated with death in COVID-19 patients (OR 1.05, 95% CI 0.65-1.71, P = 0.84, I2 = 66.6%). In dose-response analysis, it was estimated that COVID-19 patients had a 16% increased risk of invasive mechanical ventilation (OR 1.16, 95% CI 1.10-1.23, P < 0.0001) and a 20% increased risk of admission to ICU (OR 1.20, 95% CI 1.11-1.30, P < 0.0001) per 5 kg/m2 increase in BMI. In conclusion, obesity in COVID-19 patients is associated with severity, but not mortality.
  • |Body Mass Index[MESH]
  • |COVID-19/*complications/epidemiology/mortality[MESH]
  • |Hospitalization/statistics & numerical data[MESH]
  • |Humans[MESH]
  • |Obesity/*complications/epidemiology[MESH]
  • |Prevalence[MESH]
  • |Risk Factors[MESH]


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