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10.1097/MNH.0000000000000687 http://scihub22266oqcxt.onion/10.1097/MNH.0000000000000687 33395037!ä!33395037 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\33395037.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Curr+Opin+Nephrol+Hypertens 2021 ; 30 (2): 223-230 Nephropedia Template TP {{tp|p=33395037|t=2021. Sodium bicarbonate therapy for acute respiratory acidosis |pdf=|usr=}}{{33395037}} gab.com Text Sodium bicarbonate therapy for acute respiratory acidosis JO: Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=33395037 #FOAvip PURPOSE OF REVIEW: Respiratory acidosis is commonly present in patients with respiratory failure. The usual treatment of hypercapnia is to increase ventilation. During the recent surge of COVID-19, respiratory acidosis unresponsive to increased mechanical ventilatory support was common. Increasing mechanical ventilation comes at the expense of barotrauma and hemodynamic compromise from increasing positive end-expiratory pressures or minute ventilation. Treating acute respiratory acidemia with sodium bicarbonate remains controversial. RECENT FINDINGS: There are no randomized controlled trials of administration of sodium bicarbonate for respiratory acidemia. A recent review concluded that alkali therapy for mixed respiratory and metabolic acidosis might be useful but was based on the conflicting and not conclusive literature regarding metabolic acidosis. This strategy should not be extrapolated to treatment of respiratory acidemia. Low tidal volume ventilation in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) has beneficial effects associated with permissive hypercapnia. Whether the putative benefits will be negated by administration of alkali is not known. Hypercapnic acidosis is well tolerated, with few adverse effects as long as tissue perfusion and oxygenation are maintained. SUMMARY: There is a lack of clinical evidence that administration of sodium bicarbonate for respiratory acidosis has a net benefit; in fact, there are potential risks associated with it. Twit Text FOAVip Sodium bicarbonate therapy for acute respiratory acidosis ????Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=33395037 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33395037 #FOAvip English Wikipedia <ref>{{Cite pmid|33395037}}</ref> Sodium bicarbonate therapy for acute respiratory acidosis #MMPMID33395037 Chand R; Swenson ER; Goldfarb DS Curr Opin Nephrol Hypertens 2021[Mar]; 30 (2): 223-230 PMID33395037show ga PURPOSE OF REVIEW: Respiratory acidosis is commonly present in patients with respiratory failure. The usual treatment of hypercapnia is to increase ventilation. During the recent surge of COVID-19, respiratory acidosis unresponsive to increased mechanical ventilatory support was common. Increasing mechanical ventilation comes at the expense of barotrauma and hemodynamic compromise from increasing positive end-expiratory pressures or minute ventilation. Treating acute respiratory acidemia with sodium bicarbonate remains controversial. RECENT FINDINGS: There are no randomized controlled trials of administration of sodium bicarbonate for respiratory acidemia. A recent review concluded that alkali therapy for mixed respiratory and metabolic acidosis might be useful but was based on the conflicting and not conclusive literature regarding metabolic acidosis. This strategy should not be extrapolated to treatment of respiratory acidemia. Low tidal volume ventilation in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) has beneficial effects associated with permissive hypercapnia. Whether the putative benefits will be negated by administration of alkali is not known. Hypercapnic acidosis is well tolerated, with few adverse effects as long as tissue perfusion and oxygenation are maintained. SUMMARY: There is a lack of clinical evidence that administration of sodium bicarbonate for respiratory acidosis has a net benefit; in fact, there are potential risks associated with it. |Acidosis, Respiratory/*drug therapy/etiology[MESH] |Acute Disease[MESH] |COVID-19/complications/therapy[MESH] |Humans[MESH] |Respiration, Artificial[MESH] |SARS-CoV-2[MESH]Sodium bicarbonate therapy for acute respiratory acidosis (epmc).pdf DeepDyve Pubget Overpricing