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10.1097/MNH.0000000000000692 http://scihub22266oqcxt.onion/10.1097/MNH.0000000000000692 33395036!ä!33395036 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Opin+Nephrol+Hypertens 2021 ; 30 (2): 252-263 Nephropedia Template TP {{tp|p=33395036|t=2021. Angiotensin-converting enzyme 2: from a vasoactive peptide to the gatekeeper of a global pandemic |pdf=|usr=}}{{33395036}} gab.com Text Angiotensin-converting enzyme 2: from a vasoactive peptide to the gatekeeper of a global pandemic JO: Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=33395036 #FOAvip PURPOSE OF REVIEW: We provide a comprehensive overview of angiotensin-converting enzyme 2 (ACE2) as a possible candidate for pharmacological approaches to halt inflammatory processes in different pathogenic conditions. RECENT FINDINGS: ACE2 has quickly gained prominence in basic research as it has been identified as the main entry receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This novel pathogen causes Coronavirus Disease 2019 (COVID-19), a pathogenic condition that reached pandemic proportion and is associated with unprecedented morbidity and mortality. SUMMARY: The renin-angiotensin system is a complex, coordinated hormonal cascade that plays a pivotal role in controlling individual cell behaviour and multiple organ functions. ACE2 acts as an endogenous counter-regulator to the pro-inflammatory and pro-fibrotic pathways triggered by ACE through the conversion of Ang II into the vasodilatory peptide Ang 1-7. We discuss the structure, function and expression of ACE2 in different tissues. We also briefly describe the role of ACE2 as a pivotal driver across a wide spectrum of pathogenic conditions, such as cardiac and renal diseases. Furthermore, we provide the most recent data concerning the possible role of ACE2 in mediating SARS-CoV-2 infection and dictating COVID-19 severity. Twit Text FOAVip Angiotensin-converting enzyme 2: from a vasoactive peptide to the gatekeeper of a global pandemic ????Curr Opin Nephrol Hypertens http://www.kidney.de/pget.php?&tw=1&pmid=33395036 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33395036 #FOAvip English Wikipedia <ref>{{Cite pmid|33395036}}</ref> Angiotensin-converting enzyme 2: from a vasoactive peptide to the gatekeeper of a global pandemic #MMPMID33395036 Perico L; Benigni A; Remuzzi G Curr Opin Nephrol Hypertens 2021[Mar]; 30 (2): 252-263 PMID33395036show ga PURPOSE OF REVIEW: We provide a comprehensive overview of angiotensin-converting enzyme 2 (ACE2) as a possible candidate for pharmacological approaches to halt inflammatory processes in different pathogenic conditions. RECENT FINDINGS: ACE2 has quickly gained prominence in basic research as it has been identified as the main entry receptor for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This novel pathogen causes Coronavirus Disease 2019 (COVID-19), a pathogenic condition that reached pandemic proportion and is associated with unprecedented morbidity and mortality. SUMMARY: The renin-angiotensin system is a complex, coordinated hormonal cascade that plays a pivotal role in controlling individual cell behaviour and multiple organ functions. ACE2 acts as an endogenous counter-regulator to the pro-inflammatory and pro-fibrotic pathways triggered by ACE through the conversion of Ang II into the vasodilatory peptide Ang 1-7. We discuss the structure, function and expression of ACE2 in different tissues. We also briefly describe the role of ACE2 as a pivotal driver across a wide spectrum of pathogenic conditions, such as cardiac and renal diseases. Furthermore, we provide the most recent data concerning the possible role of ACE2 in mediating SARS-CoV-2 infection and dictating COVID-19 severity. |Angiotensin-Converting Enzyme 2/genetics/*metabolism[MESH] |Angiotensin-Converting Enzyme Inhibitors/therapeutic use[MESH] |COVID-19 Drug Treatment[MESH] |COVID-19/*enzymology[MESH] |Humans[MESH] |Renin-Angiotensin System/drug effects[MESH]Angiotensin-converting enzyme 2: from a vasoactive peptide to the gate(epmc).pdf DeepDyve Pubget Overpricing