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10.1007/s12250-020-00327-x

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33394351!7779898!33394351
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suck abstract from ncbi


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pmid33394351      Virol+Sin 2020 ; 35 (6): 713-724
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  • Human Monoclonal Antibodies: On the Menu of Targeted Therapeutics Against COVID-19 #MMPMID33394351
  • Chen J; Huang R; Nie Y; Wen X; Wu Y
  • Virol Sin 2020[Dec]; 35 (6): 713-724 PMID33394351show ga
  • Coronavirus disease 2019 (COVID-19), reminiscent of the severe acute respiratory syndrome (SARS) outbreak in 2003, has been a tragic disaster to people all over the world. As there is no specific drug for COVID-19, neutralizing antibodies are attracting more and more attention as one of the most effective means to combat the pandemic. Here, we introduced the etiological and serological characteristics of COVID-19, discussed the current stage of development of human monoclonal antibodies against SARS-CoV-2 and summarized the antigenic epitopes in the S glycoprotein, which may deepen the understanding of the profile of immune recognition and response against SARS-CoV-2 and provide insight for the design of effective vaccines and antibody-based therapies.
  • |*COVID-19 Drug Treatment[MESH]
  • |Animals[MESH]
  • |Antibodies, Monoclonal/immunology/*therapeutic use[MESH]
  • |Antibodies, Neutralizing/immunology/*therapeutic use[MESH]
  • |Antibodies, Viral/immunology[MESH]
  • |Antigens, Viral/chemistry/immunology[MESH]
  • |COVID-19/*immunology[MESH]
  • |Epitopes/immunology[MESH]
  • |Humans[MESH]
  • |Neutralization Tests[MESH]
  • |Pandemics[MESH]
  • |SARS-CoV-2/*immunology[MESH]


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