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10.1007/s00702-020-02283-y

http://scihub22266oqcxt.onion/10.1007/s00702-020-02283-y
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33392827!7779096!33392827
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suck abstract from ncbi


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pmid33392827      J+Neural+Transm+(Vienna) 2021 ; 128 (1): 37-48
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  • Characteristic of Parkinson s disease with severe COVID-19: a study of 10 cases from Wuhan #MMPMID33392827
  • Zhai H; Lv Y; Xu Y; Wu Y; Zeng W; Wang T; Cao X; Xu Y
  • J Neural Transm (Vienna) 2021[Jan]; 128 (1): 37-48 PMID33392827show ga
  • Information about Parkinson's disease (PD) patients with severe COVID-19 is scarce. We aimed to analyze the clinical characteristics, outcomes, and risk factors affecting the prognosis of PD patients with severe COVID-19 infection. Clinical data of severe COVID-19 patients admitted at the Union Hospital, Wuhan between 28th January and 29th February 2020 were collected and analyzed. 10 patients (1.96%) had a medical history of PD with a mean (SD) age of 72.10 (+/- 11.46) years. The clinical characteristics and outcomes of severe COVID-19 with and without PD patients were then compared. There was no significant difference in overall mortality between the PD and non-PD patients with severe COVID-19 (p > 0.05). In PD patients with severe COVID-19, the proportion of patients with critical type, disturbance of consciousness, incidence of complications, white blood cells count and neutrophils counts on admission seem higher in the non-survivors. PD patients with older age, longer PD duration, and late stage PD may be highly susceptible to critical COVID-19 infection and bad outcome. The PD patients with consciousness disorders and complications that progressed rapidly are at increased risk of death.
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/complications/*epidemiology/mortality[MESH]
  • |China/epidemiology[MESH]
  • |Comorbidity[MESH]
  • |Consciousness Disorders/*epidemiology/etiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Parkinson Disease/*epidemiology/mortality[MESH]
  • |Retrospective Studies[MESH]
  • |Risk Factors[MESH]


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