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10.1016/j.heliyon.2020.e05850 http://scihub22266oqcxt.onion/10.1016/j.heliyon.2020.e05850 33392409!7762714!33392409     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Heliyon 2021 ; 7 (1): e05850 Nephropedia Template TP {{tp|p=33392409|t=2021. Atlas of ACE2 gene expression reveals novel insights into transmission of SARS-CoV-2 |pdf=|usr=}}{{33392409}} gab.com Text Atlas of ACE2 gene expression reveals novel insights into transmission of SARS-CoV-2 JO: Heliyon http://www.kidney.de/pget.php?&tw=1&pmid=33392409 #FOAvip The recent pandemic, COVID-19, is caused by a novel coronavirus, SARS-CoV-2, with elusive origin. SARS-CoV-2 infects mammalian cells via ACE2, a transmembrane protein. Therefore, the conservation and expression patterns of ACE2 may provide valuable insights into tracing the carriers of SARS-CoV-2. In this work, we analyzed the conservation of ACE2 and its expression pattern among various mammalian species that are close to human beings. We show that mammalian ACE2 gene is deeply conserved at both DNA and peptide levels, suggesting that a broad range of mammals can potentially host SARS-CoV-2. We further report that ACE2 expression in certain human tissues are consistent with clinical symptoms of COVID-19 patients. Furthermore, we have built the first atlas of ACE2 expression in various common mammals, which shows that ACE2 expresses in mammalian tissues in a species-specific manner. Most notably, we observe exceptionally high expression of ACE2 in external body parts of cats and dogs, suggesting that these household pet animals could be vulnerable to viral infections and/or may serve as intermediate hosts, thus yielding novel insights into the transmission of SARS-CoV-2. Twit Text FOAVip Atlas of ACE2 gene expression reveals novel insights into transmission of SARS-CoV-2 ????Heliyon http://www.kidney.de/pget.php?&tw=1&pmid=33392409 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33392409 #FOAvip English Wikipedia <ref>{{Cite pmid|33392409}}</ref> Atlas of ACE2 gene expression reveals novel insights into transmission of SARS-CoV-2 #MMPMID33392409 Sun K; Gu L; Ma L; Duan Y Heliyon 2021[Jan]; 7 (1): e05850 PMID33392409show ga The recent pandemic, COVID-19, is caused by a novel coronavirus, SARS-CoV-2, with elusive origin. SARS-CoV-2 infects mammalian cells via ACE2, a transmembrane protein. Therefore, the conservation and expression patterns of ACE2 may provide valuable insights into tracing the carriers of SARS-CoV-2. In this work, we analyzed the conservation of ACE2 and its expression pattern among various mammalian species that are close to human beings. We show that mammalian ACE2 gene is deeply conserved at both DNA and peptide levels, suggesting that a broad range of mammals can potentially host SARS-CoV-2. We further report that ACE2 expression in certain human tissues are consistent with clinical symptoms of COVID-19 patients. Furthermore, we have built the first atlas of ACE2 expression in various common mammals, which shows that ACE2 expresses in mammalian tissues in a species-specific manner. Most notably, we observe exceptionally high expression of ACE2 in external body parts of cats and dogs, suggesting that these household pet animals could be vulnerable to viral infections and/or may serve as intermediate hosts, thus yielding novel insights into the transmission of SARS-CoV-2. äAtlas of ACE2 gene expression reveals novel insights into transmission(epmc).pdf DeepDyve Pubget Overpricing