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10.12998/wjcc.v8.i24.6252 http://scihub22266oqcxt.onion/10.12998/wjcc.v8.i24.6252 33392306!7760445!33392306     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       World+J+Clin+Cases 2020 ; 8 (24): 6252-6263 Nephropedia Template TP {{tp|p=33392306|t=2020. Virus load and virus shedding of SARS-CoV-2 and their impact on patient outcomes |pdf=|usr=}}{{33392306}} gab.com Text Virus load and virus shedding of SARS-CoV-2 and their impact on patient outcomes JO: World J Clin Cases http://www.kidney.de/pget.php?&tw=1&pmid=33392306 #FOAvip BACKGROUND: Understanding a virus shedding patterns in body fluids/secretions is important to determine the samples to be used for diagnosis and to formulate infection control measures. AIM: To investigate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding patterns and its risk factors. METHODS: All laboratory-confirmed coronavirus disease 2019 patients with complete medical records admitted to the Shenzhen Third People's Hospital from January 28, 2020 to March 8, 2020 were included. Among 145 patients (54.5% males; median age, 46.1 years), three (2.1%) died. The bronco-alveolar lavage fluid (BALF) had the highest virus load compared with the other samples. The viral load peaked at admission (3.3 x 10(8) copies) and sharply decreased 10 d after admission. RESULTS: The viral load was associated with prolonged intensive care unit (ICU) duration. Patients in the ICU had significantly longer shedding time compared to those in the wards (P < 0.0001). Age > 60 years [hazard ratio (HR) = 0.6; 95% confidence interval (CI): 0.4-0.9] was an independent risk factor for SARS-CoV-2 shedding, while chloroquine (HR = 22.8; 95%CI: 2.3-224.6) was a protective factor. CONCLUSION: BALF had the highest SARS-CoV-2 load. Elderly patients had higher virus loads, which was associated with a prolonged ICU stay. Chloroquine was associated with shorter shedding duration and increased the chance of viral negativity. Twit Text FOAVip Virus load and virus shedding of SARS-CoV-2 and their impact on patient outcomes ????World J Clin Cases http://www.kidney.de/pget.php?&tw=1&pmid=33392306 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33392306 #FOAvip English Wikipedia <ref>{{Cite pmid|33392306}}</ref> Virus load and virus shedding of SARS-CoV-2 and their impact on patient outcomes #MMPMID33392306 Chen PF; Yu XX; Liu YP; Ren D; Shen M; Huang BS; Gao JL; Huang ZY; Wu M; Wang WY; Chen L; Shi X; Wang ZQ; Liu YX; Liu L; Liu Y World J Clin Cases 2020[Dec]; 8 (24): 6252-6263 PMID33392306show ga BACKGROUND: Understanding a virus shedding patterns in body fluids/secretions is important to determine the samples to be used for diagnosis and to formulate infection control measures. AIM: To investigate the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) shedding patterns and its risk factors. METHODS: All laboratory-confirmed coronavirus disease 2019 patients with complete medical records admitted to the Shenzhen Third People's Hospital from January 28, 2020 to March 8, 2020 were included. Among 145 patients (54.5% males; median age, 46.1 years), three (2.1%) died. The bronco-alveolar lavage fluid (BALF) had the highest virus load compared with the other samples. The viral load peaked at admission (3.3 x 10(8) copies) and sharply decreased 10 d after admission. RESULTS: The viral load was associated with prolonged intensive care unit (ICU) duration. Patients in the ICU had significantly longer shedding time compared to those in the wards (P < 0.0001). Age > 60 years [hazard ratio (HR) = 0.6; 95% confidence interval (CI): 0.4-0.9] was an independent risk factor for SARS-CoV-2 shedding, while chloroquine (HR = 22.8; 95%CI: 2.3-224.6) was a protective factor. CONCLUSION: BALF had the highest SARS-CoV-2 load. Elderly patients had higher virus loads, which was associated with a prolonged ICU stay. Chloroquine was associated with shorter shedding duration and increased the chance of viral negativity. äVirus load and virus shedding of SARS-CoV-2 and their impact on patien(epmc).pdf DeepDyve Pubget Overpricing