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10.12688/f1000research.27287.2 http://scihub22266oqcxt.onion/10.12688/f1000research.27287.2 33391730!7745182!33391730     free     free     free Warning: Undefined variable $yww in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 538 Warning: Undefined variable $yww in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 538       F1000Res 2020 ; 9 (ä): 1349 Nephropedia Template TP {{tp|p=33391730|t=2020. The long tail of Covid-19 - The detection of a prolonged inflammatory response after a SARS-CoV-2 infection in asymptomatic and mildly affected patients |pdf=|usr=}}{{33391730}} gab.com Text The long tail of Covid-19 - The detection of a prolonged inflammatory response after a SARS-CoV-2 infection in asymptomatic and mildly affected patients JO: F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=33391730 #FOAvip 'Long Covid', or medical complications associated with post SARS-CoV-2 infection, is a significant post-viral complication that is being more and more commonly reported in patients. Therefore, there is an increasing need to understand the disease mechanisms, identify drug targets and inflammatory processes associated with a SARS-CoV-2 infection. To address this need, we created a targeted mass spectrometry based multiplexed panel of 96 immune response associated proteins. We applied the multiplex assay to a cohort of serum samples from asymptomatic and moderately affected patients. All patients had tested positive for a SARS-CoV-2 infection by PCR and were determined to be subsequently positive for antibodies. Even 40-60 days post-viral infection, we observed a significant remaining inflammatory response in all patients. Proteins that were still affected were associated with the anti-inflammatory response and mitochondrial stress. This indicates that biochemical and inflammatory pathways within the body can remain perturbed long after SARS-CoV-2 infections have subsided even in asymptomatic and moderately affected patients. Twit Text FOAVip The long tail of Covid-19 - The detection of a prolonged inflammatory response after a SARS-CoV-2 infection in asymptomatic and mildly affected patients ????F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=33391730 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33391730 #FOAvip English Wikipedia <ref>{{Cite pmid|33391730}}</ref> The long tail of Covid-19 - The detection of a prolonged inflammatory response after a SARS-CoV-2 infection in asymptomatic and mildly affected patients #MMPMID33391730 Doykov I; Hallqvist J; Gilmour KC; Grandjean L; Mills K; Heywood WE F1000Res 2020[]; 9 (ä): 1349 PMID33391730show ga 'Long Covid', or medical complications associated with post SARS-CoV-2 infection, is a significant post-viral complication that is being more and more commonly reported in patients. Therefore, there is an increasing need to understand the disease mechanisms, identify drug targets and inflammatory processes associated with a SARS-CoV-2 infection. To address this need, we created a targeted mass spectrometry based multiplexed panel of 96 immune response associated proteins. We applied the multiplex assay to a cohort of serum samples from asymptomatic and moderately affected patients. All patients had tested positive for a SARS-CoV-2 infection by PCR and were determined to be subsequently positive for antibodies. Even 40-60 days post-viral infection, we observed a significant remaining inflammatory response in all patients. Proteins that were still affected were associated with the anti-inflammatory response and mitochondrial stress. This indicates that biochemical and inflammatory pathways within the body can remain perturbed long after SARS-CoV-2 infections have subsided even in asymptomatic and moderately affected patients. |COVID-19/*complications/*diagnosis[MESH] |Humans[MESH] |Inflammation/*virology[MESH] |Mass Spectrometry[MESH] The long tail of Covid-19 - The detection of a prolonged inflammator(epmc).pdf DeepDyve Pubget Overpricing