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10.3389/fphar.2020.604579

http://scihub22266oqcxt.onion/10.3389/fphar.2020.604579
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33390994!7773655!33390994
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suck abstract from ncbi

pmid33390994      Front+Pharmacol 2020 ; 11 (ä): 604579
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  • COVID-19 Disease and Vitamin D: A Mini-Review #MMPMID33390994
  • Boulkrane MS; Ilina V; Melchakov R; Fedotova J; Drago F; Gozzo L; Das UN; Abd El-Aty AM; Baranenko D
  • Front Pharmacol 2020[]; 11 (ä): 604579 PMID33390994show ga
  • Novel coronavirus disease (COVID-19) pandemic caused by SARS-CoV-2, for which there is no effective treatment except employing prevention strategies, has already instituted significant number of deaths. In this review, we provide a scientific view on the potential role of vitamin D in SARS-CoV-2 virus/COVID-19 disease. Vitamin D is well-known to play a significant role in maintaining the immune health of an individual. Moreover, it induces antimicrobial peptide expression that can decrease viral replication and regulate the levels of pro-inflammatory/anti-inflammatory cytokines. Therefore, supplementation of vitamin D has the potential to reduce the incidence, severity and the risk of death from pneumonia resulting from the cytokine storm of many viral infections including COVID-19. We suggest that supplementation of subjects at high risk of COVID-19 with vitamin D (1.000 to 3.000 IU) to maintain its optimum serum concentrations may be of significant benefit for both in the prevention and treatment of the COVID-19.
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