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10.7150/ijms.47706

http://scihub22266oqcxt.onion/10.7150/ijms.47706
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33390810!7757148!33390810
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suck abstract from ncbi


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pmid33390810      Int+J+Med+Sci 2021 ; 18 (2): 406-418
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  • DCs-based therapies: potential strategies in severe SARS-CoV-2 infection #MMPMID33390810
  • Han J; Sun J; Zhang G; Chen H
  • Int J Med Sci 2021[]; 18 (2): 406-418 PMID33390810show ga
  • Pneumonia caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is spreading globally. There have been strenuous efforts to reveal the mechanisms that the host defends itself against invasion by this virus. The immune system could play a crucial role in virus infection. Dendritic cell as sentinel of the immune system plays an irreplaceable role. Dendritic cells-based therapeutic approach may be a potential strategy for SARS-CoV-2 infection. In this review, the characteristics of coronavirus are described briefly. We focus on the essential functions of dendritic cell in severe SARS-CoV-2 infection. Basis of treatment based dendritic cells to combat coronavirus infections is summarized. Finally, we propose that the combination of DCs based vaccine and other therapy is worth further study.
  • |*Dendritic Cells[MESH]
  • |*Immunotherapy[MESH]
  • |COVID-19/immunology/*therapy[MESH]
  • |Clinical Trials as Topic[MESH]
  • |Host-Pathogen Interactions[MESH]
  • |Humans[MESH]


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