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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Intern+Med 2021 ; 60 (4): 639-643 Nephropedia Template TP
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Immediate Amelioration of Severe Respiratory Distress in Sjogren s Syndrome with COVID-19 Treated with a Single Dose of Off-label Tocilizumab #MMPMID33390490
Kataoka H; Kodama F; Tomita T; Kondo M; Nagasaka A; Nishikawa S; Mukai M
Intern Med 2021[Feb]; 60 (4): 639-643 PMID33390490show ga
The coronavirus disease 2019 (COVID-19) pandemic has become an urgent global health issue. An older age and underlying conditions, such as diabetes, have been reported as risk factors, but whether or not autoimmune diseases increase the risk remains unknown. An 85-year-old man with Sjogren's syndrome developed a severe COVID-19 infection that required oxygen supplementation. After discussing the goals of care with him and his wife, off-label tocilizumab was given concomitantly, resulting in a rapid improvement in his symptoms and respiratory failure. This patient represents a supplementary case confirming the efficacy and safety of tocilizumab for COVID-19 in elderly patients with autoimmune diseases.