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10.1016/j.diabet.2020.101222

http://scihub22266oqcxt.onion/10.1016/j.diabet.2020.101222
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suck abstract from ncbi


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pmid33388386      Diabetes+Metab 2021 ; 47 (4): 101222
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  • Association of diabetes and outcomes in patients with COVID-19: Propensity score-matched analyses from a French retrospective cohort #MMPMID33388386
  • Sutter W; Duceau B; Vignac M; Bonnet G; Carlier A; Roussel R; Trimaille A; Pommier T; Guilleminot P; Sagnard A; Pastier J; Weizman O; Giordano G; Cellier J; Geneste L; Panagides V; Marsou W; Deney A; Karsenty C; Attou S; Delmotte T; Ribeyrolles S; Chemaly P; Gautier A; Fauvel C; Chaumont C; Mika D; Pezel T; Cohen A; Potier L
  • Diabetes Metab 2021[Jul]; 47 (4): 101222 PMID33388386show ga
  • BACKGROUND: Our study aimed to compare the clinical outcomes of patients with and without diabetes admitted to hospital with COVID-19. METHODS: This retrospective multicentre cohort study comprised 24 tertiary medical centres in France, and included 2851 patients (675 with diabetes) hospitalized for COVID-19 between 26 February and 20 April 2020. A propensity score-matching (PSM) method (1:1 matching including patients' characteristics, medical history, vital statistics and laboratory results) was used to compare patients with and without diabetes (n = 603 per group). The primary outcome was admission to an intensive care unit (ICU) and/or in-hospital death. RESULTS: After PSM, all baseline characteristics were well balanced between those with and without diabetes: mean age was 71.2 years; 61.8% were male; and mean BMI was 29 kg/m(2). A history of cardiovascular, chronic kidney and chronic obstructive pulmonary diseases were found in 32.8%, 22.1% and 6.4% of participants, respectively. The risk of experiencing the primary outcome was similar in patients with or without diabetes [hazard ratio (HR): 1.16, 95% confidence interval (CI): 0.95-1.41; P = 0.14], and was 1.29 (95% CI: 0.97-1.69) for in-hospital death, 1.26 (95% CI: 0.9-1.72) for death with no transfer to an ICU and 1.14 (95% CI: 0.88-1.47) with transfer to an ICU. CONCLUSION: In this retrospective study cohort of patients hospitalized for COVID-19, diabetes was not significantly associated with a higher risk of severe outcomes after PSM. TRIAL REGISTRATION NUMBER: NCT04344327.
  • |*Hospital Mortality[MESH]
  • |*Intensive Care Units[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*epidemiology/mortality/physiopathology[MESH]
  • |Comorbidity[MESH]
  • |Diabetes Mellitus/*epidemiology[MESH]
  • |Female[MESH]
  • |France/epidemiology[MESH]
  • |Humans[MESH]
  • |Length of Stay[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Patient Transfer/*statistics & numerical data[MESH]
  • |Propensity Score[MESH]
  • |Retrospective Studies[MESH]


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