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10.1007/s15010-020-01556-8

http://scihub22266oqcxt.onion/10.1007/s15010-020-01556-8
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33387262!7776280!33387262
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suck abstract from ncbi


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pmid33387262      Infection 2021 ; 49 (4): 781-783
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  • Differential serological and neutralizing antibody dynamics after an infection by a single SARS-CoV-2 strain #MMPMID33387262
  • Billon-Denis E; Ferrier-Rembert A; Garnier A; Cheutin L; Vigne C; Tessier E; Denis J; Badaut C; Rougeaux C; Depeille Wuille A; Timera H; Boutin LI; Drouet I; Verguet N; Nolent F; Gorge O; Ferraris O; Tournier JN
  • Infection 2021[Aug]; 49 (4): 781-783 PMID33387262show ga
  • BACKGROUND: We report here the case of two coworkers infected by the same SARS-CoV-2 strain, presenting two different immunological outcomes. CASE: One patient presented a strong IgG anti-receptor-binding domain immune response correlated with a low and rapidly decreasing titer of neutralizing antibodies. The other patient had a similar strong IgG anti-receptor-binding domain immune response but high neutralizing antibody titers. DISCUSSION AND CONCLUSION: Thus, host individual factors may be the main drivers of the immune response varying with age and clinical severity.
  • |*Infectious Disease Transmission, Patient-to-Professional[MESH]
  • |Adult[MESH]
  • |Antibodies, Neutralizing/biosynthesis/*blood[MESH]
  • |Antibodies, Viral/*blood[MESH]
  • |COVID-19/*immunology/transmission[MESH]
  • |Cross Infection/immunology[MESH]
  • |Enzyme-Linked Immunosorbent Assay[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/biosynthesis/*blood[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Nasopharynx/virology[MESH]


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