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10.1016/j.drudis.2020.12.010 http://scihub22266oqcxt.onion/10.1016/j.drudis.2020.12.010 33385574!7771376!33385574     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Drug+Discov+Today 2021 ; 26 (3): 631-636 Nephropedia Template TP {{tp|p=33385574|t=2021. Why do we lack a specific magic anti-COVID-19 drug? Analyses and solutions |pdf=|usr=}}{{33385574}} gab.com Text Why do we lack a specific magic anti-COVID-19 drug Analyses and solutions JO: Drug Discov Today http://www.kidney.de/pget.php?&tw=1&pmid=33385574 #FOAvip The Coronavirus 2019 (COVID-19) pandemic represents the greatest worldwide public health crisis of recent times. The lack of proven effective therapies means that COVID-19 rages relatively unchecked. Current anti-COVID-19 pharmacotherapies are drugs originally designed for other diseases, and administered orally or intravascularly. Thus, they can have various adverse effects. A specific anti-Coronavirus drug should not only target the virus per se, but also treat the related respiratory and cardiovascular symptoms. Here, we examine the advantages and disadvantages of current anti-COVID-19 pharmacotherapies, and analyze the reasons why in the era of big data we have not yet established specific coronavirus therapies and related technical bottlenecks. Finally, we present our design of a novel nebulized S-nitrosocaptopril that is under development for targeting both coronaviruses and their related symptoms. Twit Text FOAVip Why do we lack a specific magic anti-COVID-19 drug Analyses and solutions ????Drug Discov Today http://www.kidney.de/pget.php?&tw=1&pmid=33385574 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33385574 #FOAvip English Wikipedia <ref>{{Cite pmid|33385574}}</ref> Why do we lack a specific magic anti-COVID-19 drug? Analyses and solutions #MMPMID33385574 Lin M; Dong HY; Xie HZ; Li YM; Jia L Drug Discov Today 2021[Mar]; 26 (3): 631-636 PMID33385574show ga The Coronavirus 2019 (COVID-19) pandemic represents the greatest worldwide public health crisis of recent times. The lack of proven effective therapies means that COVID-19 rages relatively unchecked. Current anti-COVID-19 pharmacotherapies are drugs originally designed for other diseases, and administered orally or intravascularly. Thus, they can have various adverse effects. A specific anti-Coronavirus drug should not only target the virus per se, but also treat the related respiratory and cardiovascular symptoms. Here, we examine the advantages and disadvantages of current anti-COVID-19 pharmacotherapies, and analyze the reasons why in the era of big data we have not yet established specific coronavirus therapies and related technical bottlenecks. Finally, we present our design of a novel nebulized S-nitrosocaptopril that is under development for targeting both coronaviruses and their related symptoms. |*Antiviral Agents/classification/pharmacology[MESH] |*COVID-19 Drug Treatment[MESH] |*COVID-19/epidemiology/physiopathology/virology[MESH] |Angiotensin-Converting Enzyme Inhibitors/pharmacology[MESH] |Captopril/*analogs & derivatives/pharmacology[MESH] |Cardiovascular System/drug effects/metabolism[MESH] |Drug Development/methods[MESH] |Drug Repositioning/methods[MESH] |Humans[MESH] |Nebulizers and Vaporizers[MESH] |Pharmaceutical Preparations[MESH] |Respiratory System/diagnostic imaging/metabolism[MESH] |SARS-CoV-2/drug effects/physiology[MESH]Why do we lack a specific magic anti-COVID-19 drug? Analyses and solut(epmc).pdf DeepDyve Pubget Overpricing