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10.15585/mmwr.mm695152e1

http://scihub22266oqcxt.onion/10.15585/mmwr.mm695152e1
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33382675!9191904!33382675
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suck abstract from ncbi


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pmid33382675      MMWR+Morb+Mortal+Wkly+Rep 2021 ; 69 (5152): 1653-1656
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  • The Advisory Committee on Immunization Practices Interim Recommendation for Use of Moderna COVID-19 Vaccine - United States, December 2020 #MMPMID33382675
  • Oliver SE; Gargano JW; Marin M; Wallace M; Curran KG; Chamberland M; McClung N; Campos-Outcalt D; Morgan RL; Mbaeyi S; Romero JR; Talbot HK; Lee GM; Bell BP; Dooling K
  • MMWR Morb Mortal Wkly Rep 2021[Jan]; 69 (5152): 1653-1656 PMID33382675show ga
  • On December 18, 2020, the Food and Drug Administration (FDA) issued an Emergency Use Authorization (EUA) for the Moderna COVID-19 (mRNA-1273) vaccine (ModernaTX, Inc; Cambridge, Massachusetts), a lipid nanoparticle-encapsulated, nucleoside-modified mRNA vaccine encoding the stabilized prefusion spike glycoprotein of SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19) (1). This vaccine is the second COVID-19 vaccine authorized under an EUA for the prevention of COVID-19 in the United States (2). Vaccination with the Moderna COVID-19 vaccine consists of 2 doses (100 mug, 0.5 mL each) administered intramuscularly, 1 month (4 weeks) apart. On December 19, 2020, the Advisory Committee on Immunization Practices (ACIP) issued an interim recommendation* for use of the Moderna COVID-19 vaccine in persons aged >/=18 years for the prevention of COVID-19. To guide its deliberations regarding the vaccine, ACIP employed the Evidence to Recommendation (EtR) Framework,(dagger) using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach.( section sign) Use of all COVID-19 vaccines authorized under an EUA, including the Moderna COVID-19 vaccine, should be implemented in conjunction with ACIP's interim recommendations for allocating initial supplies of COVID-19 vaccines (3). The ACIP recommendation for the use of the Moderna COVID-19 vaccine under EUA is interim and will be updated as additional information becomes available.
  • |*Practice Guidelines as Topic[MESH]
  • |Adolescent[MESH]
  • |Adult[MESH]
  • |Adverse Drug Reaction Reporting Systems[MESH]
  • |Advisory Committees[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19 Vaccines/*administration & dosage/adverse effects[MESH]
  • |COVID-19/epidemiology/*prevention & control[MESH]
  • |Centers for Disease Control and Prevention, U.S.[MESH]
  • |Clinical Trials, Phase III as Topic[MESH]
  • |Drug Approval[MESH]
  • |Emergencies[MESH]
  • |Humans[MESH]
  • |Immunization/*standards[MESH]
  • |Middle Aged[MESH]
  • |Randomized Controlled Trials as Topic[MESH]
  • |United States Food and Drug Administration[MESH]
  • |United States/epidemiology[MESH]


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