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10.12122/j.issn.1673-4254.2020.12.22

http://scihub22266oqcxt.onion/10.12122/j.issn.1673-4254.2020.12.22
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33380405!7835685!33380405
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suck abstract from ncbi


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pmid33380405      Nan+Fang+Yi+Ke+Da+Xue+Xue+Bao 2020 ; 40 (12): 1838-1842
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  • Progress in source tracking of SARS-CoV-2 #MMPMID33380405
  • He W; Chen Q
  • Nan Fang Yi Ke Da Xue Xue Bao 2020[Dec]; 40 (12): 1838-1842 PMID33380405show ga
  • Coronavirus disease 2019 (COVID-19) pandemic has caused a total of 55 928 327 confirmed cases and 1 344 003 deaths as of November 19, 2020. But so far the origin of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes this pandemic has remained undetermined. The purpose of this study is to review the current research of SARS-CoV-2 and the existing problems therein, which may provide inspiration for further researches. Existing evidence suggested that SARS-CoV-2 may be derived from bat coronavirus 40-70 years ago. During the evolution, this virus underwent extensive variations in the process of mutations and natural selection. Different genomic regions of SARS-CoV-2 may have different selection pressures, but all of which increase the difficulty of tracing the origin of this virus. A wide variety of animals have been considered as potential hosts of SARS-CoV-2, including cats, lions, tigers, dogs and minks. SARS-CoV-2 has a chance to transmit from humans to animals and can be transmitted among animals. Current research evidence has shown that China is not the original source of SARS-CoV-2. It is still unclear how the virus spreads to human, and efforts are still need to be made to explore the origin of SARS-CoV-2, its hosts and intermediate hosts, and the mechanism of its transmission across different species of animals.
  • |Animals[MESH]
  • |COVID-19/*transmission[MESH]
  • |Cats[MESH]
  • |China[MESH]
  • |Chiroptera/*virology[MESH]
  • |Disease Vectors[MESH]
  • |Dogs[MESH]
  • |Evolution, Molecular[MESH]
  • |Humans[MESH]


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