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10.1016/j.medcli.2020.11.004 http://scihub22266oqcxt.onion/10.1016/j.medcli.2020.11.004 33380371!7719003!33380371     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Med+Clin+(Barc) 2021 ; 156 (5): 221-228 Nephropedia Template TP {{tp|p=33380371|t=2021. Efectividad de los glucocorticoides en pacientes hospitalizados por neumonia grave por SARS-CoV-2 |pdf=|usr=}}{{33380371}} gab.com Text Efectividad de los glucocorticoides en pacientes hospitalizados por neumonia grave por SARS-CoV-2 JO: Med Clin (Barc) http://www.kidney.de/pget.php?&tw=1&pmid=33380371 #FOAvip INTRODUCTION: Several studies have reported the beneficial effect of glucocorticoids in the treatment of cytokine storm that occurs in patients with severe COVID-19. Various glucocorticoids regimens have been proposed. METHODS: Retrospective observational study that includes patients with severe SARS-CoV-2 pneumonia and compares admission to an Intensive Care Unit (ICU) or death during hospitalization in three groups of patients: no glucocorticoids treatment, use of glucocorticoids doses equivalent to less than 250mg of prednisone daily and use of equivalent doses greater than or equal to 250mg of prednisone daily. Multivariate analysis was performed using logistic regression, using the propensity index as a covariant. RESULTS: Of the 259 patients enrolled in the study, 67 (25.9%) had an unfavorable evolution, dying or requiring ICU admission. Comparative analyzes between different glucocorticoids treatments and the association with ICU admission or death were: glucocorticoids treatment (any dose) versus no glucocorticoids treatment (OR: 0.71 [0.30-1.66]), treatment with glucocorticoids (>/=250mg prednisone daily) versus no glucocorticoids treatment (OR: 0.35 [0.11-1.08]) and glucocorticoids treatment (>/=250mg prednisone daily) versus patients with glucocorticoids doses <250mg prednisone daily or without glucocorticoids treatment (OR: 0.30 [0.10-0.88]). CONCLUSION: The results of this study show that patients with severe SARS-CoV-2 pneumonia treated with glucocorticoids pulses with equivalent doses of prednisone greater than or equal to 250mg have a more favorable evolution (less mortality and less admission to ICU). Twit Text FOAVip Efectividad de los glucocorticoides en pacientes hospitalizados por neumonia grave por SARS-CoV-2 ????Med Clin (Barc) http://www.kidney.de/pget.php?&tw=1&pmid=33380371 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33380371 #FOAvip English Wikipedia <ref>{{Cite pmid|33380371}}</ref> Efectividad de los glucocorticoides en pacientes hospitalizados por neumonia grave por SARS-CoV-2 #MMPMID33380371 Pascual Pareja JF; Garcia-Caballero R; Soler Rangel L; Vazquez-Ronda MA; Roa Franco S; Navarro Jimenez G; Moreno Palanco MA; Gonzalez-Ruano P; Lopez-Menchaca R; Ruiz-Seco P; Pagan Munoz B; Gomez Gomez A; Perez-Monte B; Fuerte Martinez R; Valle Lopez JL; Munoz Blanco A; Rabago Lorite I; Martinez Martin P; Serralta San Martin G; Gomez-Cerezo JF Med Clin (Barc) 2021[Mar]; 156 (5): 221-228 PMID33380371show ga INTRODUCTION: Several studies have reported the beneficial effect of glucocorticoids in the treatment of cytokine storm that occurs in patients with severe COVID-19. Various glucocorticoids regimens have been proposed. METHODS: Retrospective observational study that includes patients with severe SARS-CoV-2 pneumonia and compares admission to an Intensive Care Unit (ICU) or death during hospitalization in three groups of patients: no glucocorticoids treatment, use of glucocorticoids doses equivalent to less than 250mg of prednisone daily and use of equivalent doses greater than or equal to 250mg of prednisone daily. Multivariate analysis was performed using logistic regression, using the propensity index as a covariant. RESULTS: Of the 259 patients enrolled in the study, 67 (25.9%) had an unfavorable evolution, dying or requiring ICU admission. Comparative analyzes between different glucocorticoids treatments and the association with ICU admission or death were: glucocorticoids treatment (any dose) versus no glucocorticoids treatment (OR: 0.71 [0.30-1.66]), treatment with glucocorticoids (>/=250mg prednisone daily) versus no glucocorticoids treatment (OR: 0.35 [0.11-1.08]) and glucocorticoids treatment (>/=250mg prednisone daily) versus patients with glucocorticoids doses <250mg prednisone daily or without glucocorticoids treatment (OR: 0.30 [0.10-0.88]). CONCLUSION: The results of this study show that patients with severe SARS-CoV-2 pneumonia treated with glucocorticoids pulses with equivalent doses of prednisone greater than or equal to 250mg have a more favorable evolution (less mortality and less admission to ICU). |*COVID-19 Drug Treatment[MESH] |Adolescent[MESH] |Adult[MESH] |Aged[MESH] |Anti-Inflammatory Agents/*therapeutic use[MESH] |COVID-19/complications/mortality[MESH] |Dose-Response Relationship, Drug[MESH] |Drug Administration Schedule[MESH] |Female[MESH] |Glucocorticoids/*therapeutic use[MESH] |Hospitalization[MESH] |Humans[MESH] |Logistic Models[MESH] |Male[MESH] |Middle Aged[MESH] |Retrospective Studies[MESH] |Severity of Illness Index[MESH] |Treatment Outcome[MESH]Efectividad de los glucocorticoides en pacientes hospitalizados por ne(epmc).pdf DeepDyve Pubget Overpricing