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10.3934/mbe.2020335 http://scihub22266oqcxt.onion/10.3934/mbe.2020335 33378859!ä!33378859 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Math+Biosci+Eng 2020 ; 17 (6): 6355-6389 Nephropedia Template TP {{tp|p=33378859|t=2020. Optimal control on COVID-19 eradication program in Indonesia under the effect of community awareness |pdf=|usr=}}{{33378859}} gab.com Text Optimal control on COVID-19 eradication program in Indonesia under the effect of community awareness JO: Math Biosci Eng http://www.kidney.de/pget.php?&tw=1&pmid=33378859 #FOAvip A total of more than 27 million confirmed cases of the novel coronavirus outbreak, also known as COVID-19, have been reported as of September 7, 2020. To reduce its transmission, a number of strategies have been proposed. In this study, mathematical models with nonpharmaceutical and pharmaceutical interventions were formulated and analyzed. The first model was formulated without the inclusion of community awareness. The analysis focused on investigating the mathematical behavior of the model, which can explain how medical masks, medical treatment, and rapid testing can be used to suppress the spread of COVID-19. In the second model, community awareness was taken into account, and all the interventions considered were represented as time-dependent parameters. Using the center-manifold theorem, we showed that both models exhibit forward bifurcation. The infection parameters were obtained by fitting the model to COVID-19 incidence data from three provinces in Indonesia, namely, Jakarta, West Java, and East Java. Furthermore, a global sensitivity analysis was performed to identify the most influential parameters on the number of new infections and the basic reproduction number. We found that the use of medical masks has the greatest effect in determining the number of new infections. The optimal control problem from the second model was characterized using the well-known Pontryagin's maximum principle and solved numerically. The results of a cost-effectiveness analysis showed that community awareness plays a crucial role in determining the success of COVID-19 eradication programs. Twit Text FOAVip Optimal control on COVID-19 eradication program in Indonesia under the effect of community awareness ????Math Biosci Eng http://www.kidney.de/pget.php?&tw=1&pmid=33378859 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33378859 #FOAvip English Wikipedia <ref>{{Cite pmid|33378859}}</ref> Optimal control on COVID-19 eradication program in Indonesia under the effect of community awareness #MMPMID33378859 Aldila D; Ndii MZ; Samiadji BM Math Biosci Eng 2020[Sep]; 17 (6): 6355-6389 PMID33378859show ga A total of more than 27 million confirmed cases of the novel coronavirus outbreak, also known as COVID-19, have been reported as of September 7, 2020. To reduce its transmission, a number of strategies have been proposed. In this study, mathematical models with nonpharmaceutical and pharmaceutical interventions were formulated and analyzed. The first model was formulated without the inclusion of community awareness. The analysis focused on investigating the mathematical behavior of the model, which can explain how medical masks, medical treatment, and rapid testing can be used to suppress the spread of COVID-19. In the second model, community awareness was taken into account, and all the interventions considered were represented as time-dependent parameters. Using the center-manifold theorem, we showed that both models exhibit forward bifurcation. The infection parameters were obtained by fitting the model to COVID-19 incidence data from three provinces in Indonesia, namely, Jakarta, West Java, and East Java. Furthermore, a global sensitivity analysis was performed to identify the most influential parameters on the number of new infections and the basic reproduction number. We found that the use of medical masks has the greatest effect in determining the number of new infections. The optimal control problem from the second model was characterized using the well-known Pontryagin's maximum principle and solved numerically. The results of a cost-effectiveness analysis showed that community awareness plays a crucial role in determining the success of COVID-19 eradication programs. |Algorithms[MESH] |Basic Reproduction Number[MESH] |COVID-19/*epidemiology/prevention & control/*therapy/*transmission[MESH] |Communicable Disease Control/*methods[MESH] |Cost-Benefit Analysis[MESH] |Disease Outbreaks[MESH] |Health Education/*methods[MESH] |Humans[MESH] |Incidence[MESH] |Indonesia/epidemiology[MESH] |Models, Theoretical[MESH] |Personal Protective Equipment[MESH]Optimal control on COVID-19 eradication program in Indonesia under the(epmc).pdf DeepDyve Pubget Overpricing