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10.1007/s40264-020-01034-y

http://scihub22266oqcxt.onion/10.1007/s40264-020-01034-y
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33372244!7769328!33372244
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suck abstract from ncbi


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pmid33372244      Drug+Saf 2021 ; 44 (4): 405-408
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  • French Pharmacovigilance Public System and COVID-19 Pandemic #MMPMID33372244
  • Grandvuillemin A; Drici MD; Jonville-Bera AP; Micallef J; Montastruc JL
  • Drug Saf 2021[Apr]; 44 (4): 405-408 PMID33372244show ga
  • The current COVID-19 pandemic is an exceptional health situation including for drug use. As there was no known effective drug for COVID-19 at the beginning of the pandemic, different candidates were proposed. In this short article, we present the French public pharmacovigilance activities during this health crisis. Although COVID-19 is a confounding factor per se, owing to its potential for multi-organ damage including the heart and kidney, the quality of the transmitted data in adverse drug reaction reports, the timeliness of feedback from clinicians, and the real-time pharmacological and medical analysis by the French network of the regional pharmacovigilance centers made it possible to swiftly identify relevant safety signals. The French National Agency of Medicine was thus able to validate the data and convey their findings very early. This decentralized organization based on medical and pharmacological evaluation of case reports has proven to be efficient and responsive in this unique and challenging healthcare emergency.
  • |*Pharmacovigilance[MESH]
  • |Adverse Drug Reaction Reporting Systems/organization & administration[MESH]
  • |Antiviral Agents/administration & dosage/adverse effects[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |France/epidemiology[MESH]
  • |Humans[MESH]
  • |Pandemics[MESH]
  • |SARS-CoV-2[MESH]


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