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10.1016/j.jpeds.2020.12.033

http://scihub22266oqcxt.onion/10.1016/j.jpeds.2020.12.033
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33358846!7836928!33358846
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suck abstract from ncbi


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pmid33358846      J+Pediatr 2021 ; 234 (ä): 27-32.e2
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  • Electrocardiographic Changes in Children with Multisystem Inflammation Associated with COVID-19: Associated with Coronavirus Disease 2019 #MMPMID33358846
  • Regan W; O'Byrne L; Stewart K; Miller O; Pushparajah K; Theocharis P; Wong J; Rosenthal E
  • J Pediatr 2021[Jul]; 234 (ä): 27-32.e2 PMID33358846show ga
  • OBJECTIVE: To analyze findings and trends on serial electrocardiograms (ECGs) in multisystem inflammatory syndrome in children (MIS-C) associated with coronavirus disease taken during the course of illness and at follow-up. STUDY DESIGN: We included all children presenting with MIS-C at a single center with 3 or more ECGs taken during the course of their illness. We measured ECG intervals (PR, QRSd, and QTc) and amplitudes (R-, S-, and T-waves) on each ECG and documented any arrhythmias and ST-segment changes. RESULTS: A majority of children (n = 42, 67%) showed ECG changes. The most common findings were low QRS amplitudes and transient T-wave inversion. ST changes were uncommon and included ST-segment elevation consistent with pericarditis in 1 child and acute coronary ischemia in 1 child. Arrhythmias were seen in 13 children (21%) but were benign with the exception of 1 child who was compromised by an atrial tachycardia requiring support with extracorporeal membrane oxygenation. No children were found to have high-grade atrioventricular block. CONCLUSIONS: MIS-C is associated with electrocardiographic changes over the course of the illness, with low amplitude ECGs on presentation, followed by transient T-wave inversion, particularly in the precordial leads. There was a low prevalence of ST-segment changes and tachyarrhythmias.
  • |Arrhythmias, Cardiac/diagnosis/etiology/*physiopathology[MESH]
  • |COVID-19/diagnosis/epidemiology/*physiopathology[MESH]
  • |Child[MESH]
  • |Diagnosis, Differential[MESH]
  • |Electrocardiography/*methods[MESH]
  • |Female[MESH]
  • |Follow-Up Studies[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Retrospective Studies[MESH]
  • |SARS-CoV-2[MESH]


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