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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Vaccine 2021 ; 39 (4): 633-640 Nephropedia Template TP
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Key criteria for the ethical acceptability of COVID-19 human challenge studies: Report of a WHO Working Group #MMPMID33341309
Jamrozik E; Littler K; Bull S; Emerson C; Kang G; Kapulu M; Rey E; Saenz C; Shah S; Smith PG; Upshur R; Weijer C; Selgelid MJ
Vaccine 2021[Jan]; 39 (4): 633-640 PMID33341309show ga
This report of the WHO Working Group for Guidance on Human Challenge Studies in COVID-19 outlines ethical standards for COVID-19 challenge studies. It includes eight Key Criteria related to scientific justification, risk-benefit assessment, consultation and engagement, co-ordination of research, site selection, participant selection, expert review, and informed consent. The document aims to provide comprehensive guidance to scientists, research ethics committees, funders, policymakers, and regulators in deliberations regarding SARS-CoV-2 challenge studies by outlining criteria that would need to be satisfied in order for such studies to be ethically acceptable.