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10.1016/j.vaccine.2020.10.075

http://scihub22266oqcxt.onion/10.1016/j.vaccine.2020.10.075
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33341309!7598752!33341309
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suck abstract from ncbi


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pmid33341309      Vaccine 2021 ; 39 (4): 633-640
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  • Key criteria for the ethical acceptability of COVID-19 human challenge studies: Report of a WHO Working Group #MMPMID33341309
  • Jamrozik E; Littler K; Bull S; Emerson C; Kang G; Kapulu M; Rey E; Saenz C; Shah S; Smith PG; Upshur R; Weijer C; Selgelid MJ
  • Vaccine 2021[Jan]; 39 (4): 633-640 PMID33341309show ga
  • This report of the WHO Working Group for Guidance on Human Challenge Studies in COVID-19 outlines ethical standards for COVID-19 challenge studies. It includes eight Key Criteria related to scientific justification, risk-benefit assessment, consultation and engagement, co-ordination of research, site selection, participant selection, expert review, and informed consent. The document aims to provide comprehensive guidance to scientists, research ethics committees, funders, policymakers, and regulators in deliberations regarding SARS-CoV-2 challenge studies by outlining criteria that would need to be satisfied in order for such studies to be ethically acceptable.
  • |Antiviral Agents/administration & dosage[MESH]
  • |Biomedical Research/*ethics[MESH]
  • |COVID-19 Drug Treatment[MESH]
  • |COVID-19 Vaccines/*administration & dosage[MESH]
  • |COVID-19/immunology/*prevention & control/virology[MESH]
  • |Ethics Committees, Research/organization & administration[MESH]
  • |Healthy Volunteers[MESH]
  • |Human Experimentation/*ethics/legislation & jurisprudence[MESH]
  • |Humans[MESH]
  • |Informed Consent/*ethics[MESH]
  • |Patient Selection/ethics[MESH]
  • |SARS-CoV-2/drug effects/*pathogenicity[MESH]
  • |Vaccination/ethics[MESH]


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