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10.1016/j.jcv.2020.104712

http://scihub22266oqcxt.onion/10.1016/j.jcv.2020.104712
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suck abstract from ncbi


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pmid33338894      J+Clin+Virol 2021 ; 134 (ä): 104712
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  • Evaluation of rapid antigen detection kit from the WHO Emergency Use List for detecting SARS-CoV-2 #MMPMID33338894
  • Mak GCK; Lau SSY; Wong KKY; Chow NLS; Lau CS; Lam ETK; Chan RCW; Tsang DNC
  • J Clin Virol 2021[Jan]; 134 (ä): 104712 PMID33338894show ga
  • BACKGROUND: Currently, there are two rapid antigen detection (RAD) kits from the WHO Emergency Use List for detecting SARS-CoV-2. OBJECTIVE: The Panbio COVID-19 Ag Rapid Test Device was selected to evaluate the performance for detecting SARS-CoV-2. STUDY DESIGN: Analytical sensitivity for the detection of SARS-CoV-2 virus was determined by limit of detection (LOD) using RT-PCR as a reference method. Clinical sensitivity was evaluated by using respiratory specimens collected from confirmed COVID-19 patients. RESULTS: The LOD results showed that the RAD kit was 100 fold less sensitive than RT-PCR. Clinical sensitivity of the RAD kit was 68.6 % for detecting specimens from COVID-19 patients. CONCLUSIONS: The RAD kit evaluated in the present study shared similar performance with another kit from the WHO Emergency Use List, the Standard Q COVID-19 Ag. Understanding the clinical characteristics of RAD kits can guide us to decide different testing strategies in different settings.
  • |Antigens, Viral/*analysis[MESH]
  • |COVID-19 Testing/methods[MESH]
  • |COVID-19/*diagnosis/pathology/virology[MESH]
  • |Cross Reactions[MESH]
  • |Hong Kong[MESH]
  • |Humans[MESH]
  • |Limit of Detection[MESH]
  • |Nasopharynx/virology[MESH]
  • |Pharynx/virology[MESH]
  • |Reagent Kits, Diagnostic/*standards[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2/*immunology/pathogenicity[MESH]


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