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suck abstract from ncbi


10.1016/j.jaad.2020.10.060

http://scihub22266oqcxt.onion/10.1016/j.jaad.2020.10.060
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33323343!7585496!33323343
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suck abstract from ncbi


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pmid33323343      J+Am+Acad+Dermatol 2021 ; 84 (2): 408-414
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  • Mucocutaneous disease and related clinical characteristics in hospitalized children and adolescents with COVID-19 and multisystem inflammatory syndrome in children #MMPMID33323343
  • Rekhtman S; Tannenbaum R; Strunk A; Birabaharan M; Wright S; Garg A
  • J Am Acad Dermatol 2021[Feb]; 84 (2): 408-414 PMID33323343show ga
  • BACKGROUND: Little is known about mucocutaneous disease in acutely ill children and adolescents with COVID-19 and multisystem inflammatory syndrome in children (MIS-C). OBJECTIVE: To characterize mucocutaneous disease and its relation to clinical course among hospitalized patients with COVID-19 and MIS-C. METHODS: Descriptive cohort study of prospectively and consecutively hospitalized eligible patients between May 11, 2020 and June 5, 2020. RESULTS: In COVID-19 patients, 4 of 12 (33%) had rash and/or mucositis, including erythema, morbilliform pattern, and lip mucositis. In MIS-C patients, 9 of 19 (47%) had rash and/or mucositis, including erythema, morbilliform, retiform purpura, targetoid and urticarial patterns, along with acral edema, lip mucositis, tongue papillitis, and conjunctivitis. COVID-19 patients with rash had less frequent respiratory symptoms, pediatric intensive care unit admission, invasive ventilation, and shorter stay versus COVID-19 patients without rash. MIS-C patients with rash had less frequent pediatric intensive care unit admission, shock, ventilation, as well as lower levels of C-reactive protein, ferritin, D-dimer, and troponin (vs MIS-C without rash). Neutrophil-to-lymphocyte ratio was similar for patients with and without rash in both groups. None of the MIS-C patients met criteria for Kawasaki disease. LIMITATIONS: Small sample sizes. CONCLUSIONS: Mucocutaneous disease is common among children and adolescents with COVID-19 and MIS-C. Laboratory trends observed in patients with rash may prognosticate a less severe course.
  • |Adolescent[MESH]
  • |COVID-19/*complications[MESH]
  • |Child[MESH]
  • |Child, Preschool[MESH]
  • |Cohort Studies[MESH]
  • |Female[MESH]
  • |Hospitalization[MESH]
  • |Humans[MESH]
  • |Infant[MESH]
  • |Male[MESH]
  • |Mucositis/*etiology[MESH]
  • |Skin Diseases/*etiology[MESH]


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