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Incidencia de la COVID-19 en pacientes en tratamiento cronico con hidroxicloroquina #MMPMID33308853
Tejada Cifuentes F; Lloret Callejo A; Tirado Pelaez MJ; Rubio Pulido O; Ruiz-Morote Aragon M; Fernandez Urrusuno R; Munoz Carreras MI; Mendez Esteban MI; Maestre Sanchez V; Garcia Bonilla A; Paredero Dominguez JM; Arroyo Pineda V; Marco Tejon E; Romero Candel G; Fernandez Marchante AI; Marco Del Rio J; Ortiz Martin T; Lopez Sanchez P
Med Clin (Barc) 2021[Feb]; 156 (4): 166-171 PMID33308853show ga
OBJECTIVE: To analyze the incidence of Covid-19 in patients who are chronic users of hydroxychloroquine. PATIENTS AND METHODS: Cross-sectional retrospective observational multicenter study in health areas and districts from Castilla La-Mancha and Andalucia. Of the 4451 participants included in the first recruitment, 3817 with valid data were selected. The main variable of the study is the presence or absence of Covid-19 infection by clinical, serological or polymerase chain reaction diagnosis. Sociodemographic and clinical variables and treatment and concomitant comorbidities were recorded. RESULTS: 169 (4,45%) patients had Covid-19 infection, of which 12 (7.1%) died and 32 (18.9%) required hospital admission. Previous respiratory pathology was related to Covid-19 infection (P<.05). Maculopathy appears in 5.3% of patients and is significantly related to the dose of hydroxychloroquine consumed (P<.05). CONCLUSION: There is no relationship between chronic use of hydroxychloroquine and the incidence of Covid-19.