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10.1186/s13256-020-02551-1

http://scihub22266oqcxt.onion/10.1186/s13256-020-02551-1
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33308254!7729286!33308254
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suck abstract from ncbi

pmid33308254      J+Med+Case+Rep 2020 ; 14 (1): 242
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  • Detection of SARS-CoV-2 pneumonia: two case reports #MMPMID33308254
  • Seibert FS; Toma D; Bauer F; Paniskaki K; Anft M; Rohn BJ; Wang S; Racovitan D; Babel N; Westhoff TH
  • J Med Case Rep 2020[Dec]; 14 (1): 242 PMID33308254show ga
  • BACKGROUND: Developing therapeutic strategies for a SARS-CoV-2 infection is challenging, but first the correct diagnosis has to be made. Unspecific upper and lower respiratory tract symptoms can be misleading; hence, a nasopharyngeal swab test with a real-time reverse-transcription-polymerase chain reaction is of great importance. However, early viral clearing jeopardizes a sound diagnosis of COVID-19. CASE PRESENTATION: We report on two Caucasian patients who had negative pharyngeal swab tests at the onset of SARS-CoV-2 pneumonia. In one patient, the virus was not even detectable in bronchoalveolar lavage despite typical radiomorphologic changes. CONCLUSIONS: Negative PCR findings in both the pharynx and bronchoalveolar lavage do not exclude COVID-19 pneumonia. Computed tomography is a crucial diagnostic prerequisite in this context.
  • |*COVID-19 Nucleic Acid Testing[MESH]
  • |Aged, 80 and over[MESH]
  • |COVID-19/*diagnosis[MESH]
  • |False Positive Reactions[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]
  • |Reverse Transcriptase Polymerase Chain Reaction[MESH]
  • |SARS-CoV-2/*isolation & purification[MESH]


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