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Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Lancet+Infect+Dis 2021 ; 21 (4): e103-e109 Nephropedia Template TP
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The granting of emergency use designation to COVID-19 candidate vaccines: implications for COVID-19 vaccine trials #MMPMID33306980
Singh JA; Upshur REG
Lancet Infect Dis 2021[Apr]; 21 (4): e103-e109 PMID33306980show ga
An efficacious COVID-19 vaccine is currently the world's leading research priority. Several nations have indicated that if there is a compelling case for use of a vaccine before it is licensed, they would be prepared to authorise its emergency use or conditional approval on public health grounds. As of Dec 1, 2020, several developers of leading COVID-19 candidate vaccines have indicated that they have applied, or intend to apply, for emergency authorisation for their vaccines. Should candidate vaccines attain emergency use designation and be programmatically deployed before their phase 3 trials conclude, such a strategy could have far reaching consequences for COVID-19 vaccine research and the effective control of the COVID-19 pandemic. These issues merit careful consideration.