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10.2174/1874306402014010032 http://scihub22266oqcxt.onion/10.2174/1874306402014010032 33299490!7705954!33299490     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Open+Respir+Med+J 2020 ; 14 (ä): 32-37 Nephropedia Template TP {{tp|p=33299490|t=2020. COVID-19: A Therapeutic Approach Based on Pathophysiological Staging |pdf=|usr=}}{{33299490}} gab.com Text COVID-19: A Therapeutic Approach Based on Pathophysiological Staging JO: Open Respir Med J http://www.kidney.de/pget.php?&tw=1&pmid=33299490 #FOAvip The COVID-19 pandemic is a recently emerging problem. This has caused that the knowledge of the disease has been progressive and, therefore, the therapeutic decisions have been conditioned by this lack of knowledge on the one hand and by the therapeutic limitations on the other. Many published studies are methodologically weak and their conclusions, of limited value, have contributed to creating confusion on the therapeutic approach of the disease. In the present paper, we propose a therapeutic approach based on a new disease staging. The therapeutic approach is divided into two big sections: the pharmacological treatment for the phase of viral replication, cytokine storm or late respiratory events (which includes the adult respiratory distress syndrome (ARDS)) and the treatment of the respiratory failure In every stage, we discuss the pathophysiology and comment (accept or rule out) the pharmacological options according to the present evidence. Moreover, we indicate how respiratory failure should be treated. Some characteristics are based on the evidence found in the literature. Others are the result of my experience in other situations. Twit Text FOAVip COVID-19: A Therapeutic Approach Based on Pathophysiological Staging ????Open Respir Med J http://www.kidney.de/pget.php?&tw=1&pmid=33299490 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33299490 #FOAvip English Wikipedia <ref>{{Cite pmid|33299490}}</ref> COVID-19: A Therapeutic Approach Based on Pathophysiological Staging #MMPMID33299490 Domingo Ribas C Open Respir Med J 2020[]; 14 (ä): 32-37 PMID33299490show ga The COVID-19 pandemic is a recently emerging problem. This has caused that the knowledge of the disease has been progressive and, therefore, the therapeutic decisions have been conditioned by this lack of knowledge on the one hand and by the therapeutic limitations on the other. Many published studies are methodologically weak and their conclusions, of limited value, have contributed to creating confusion on the therapeutic approach of the disease. In the present paper, we propose a therapeutic approach based on a new disease staging. The therapeutic approach is divided into two big sections: the pharmacological treatment for the phase of viral replication, cytokine storm or late respiratory events (which includes the adult respiratory distress syndrome (ARDS)) and the treatment of the respiratory failure In every stage, we discuss the pathophysiology and comment (accept or rule out) the pharmacological options according to the present evidence. Moreover, we indicate how respiratory failure should be treated. Some characteristics are based on the evidence found in the literature. Others are the result of my experience in other situations. äCOVID-19: A Therapeutic Approach Based on Pathophysiological Staging (epmc).pdf DeepDyve Pubget Overpricing