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10.1038/s41598-020-78588-5 http://scihub22266oqcxt.onion/10.1038/s41598-020-78588-5 33293607!7722718!33293607     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2020 ; 10 (1): 21448 Nephropedia Template TP {{tp|p=33293607|t=2020. In vitro synergy of isavuconazole in combination with colistin against Candida auris |pdf=|usr=}}{{33293607}} gab.com Text In vitro synergy of isavuconazole in combination with colistin against Candida auris JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33293607 #FOAvip The in vitro interactions of isavuconazole with colistin were evaluated against 15 clinical Candida auris isolates by a microdilution checkerboard technique based on the EUCAST reference method for antifungal susceptibility testing and by agar diffusion using isavuconazole gradient concentration strips with or without colistin incorporated RPMI agar. Interpretation of the checkerboard results was done by the fractional inhibitory concentration index and by response surface analysis based on the Bliss model. By checkerboard, combination was synergistic for 93% of the isolates when interpretation of the data was done by fractional inhibitory concentration index, and for 80% of the isolates by response surface analysis interpretation. By agar diffusion test, although all MICs in combination decreased compared to isavuconazole alone, only 13% of the isolates met the definition of synergy. Essential agreement of EUCAST and gradient concentration strip MICs at +/- 2 log(2) dilutions was 93.3%. Antagonistic interactions were never observed for any technique or interpretation model used. Twit Text FOAVip In vitro synergy of isavuconazole in combination with colistin against Candida auris ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=33293607 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33293607 #FOAvip English Wikipedia <ref>{{Cite pmid|33293607}}</ref> In vitro synergy of isavuconazole in combination with colistin against Candida auris #MMPMID33293607 Schwarz P; Bidaud AL; Dannaoui E Sci Rep 2020[Dec]; 10 (1): 21448 PMID33293607show ga The in vitro interactions of isavuconazole with colistin were evaluated against 15 clinical Candida auris isolates by a microdilution checkerboard technique based on the EUCAST reference method for antifungal susceptibility testing and by agar diffusion using isavuconazole gradient concentration strips with or without colistin incorporated RPMI agar. Interpretation of the checkerboard results was done by the fractional inhibitory concentration index and by response surface analysis based on the Bliss model. By checkerboard, combination was synergistic for 93% of the isolates when interpretation of the data was done by fractional inhibitory concentration index, and for 80% of the isolates by response surface analysis interpretation. By agar diffusion test, although all MICs in combination decreased compared to isavuconazole alone, only 13% of the isolates met the definition of synergy. Essential agreement of EUCAST and gradient concentration strip MICs at +/- 2 log(2) dilutions was 93.3%. Antagonistic interactions were never observed for any technique or interpretation model used. |Agar[MESH] |Antifungal Agents/*pharmacology[MESH] |Candida/*drug effects/isolation & purification[MESH] |Candidiasis/microbiology[MESH] |Colistin/*pharmacology[MESH] |Colony Count, Microbial[MESH] |Drug Synergism[MESH] |Humans[MESH] |Microbial Sensitivity Tests[MESH] |Nitriles/*pharmacology[MESH] |Pyridines/*pharmacology[MESH]In vitro synergy of isavuconazole in combination with colistin against(epmc).pdf DeepDyve Pubget Overpricing