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10.3390/microorganisms8121929

http://scihub22266oqcxt.onion/10.3390/microorganisms8121929
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33291791!7762070!33291791
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suck abstract from ncbi


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pmid33291791      Microorganisms 2020 ; 8 (12): ä
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  • Eosinopenia in COVID-19 Patients: A Retrospective Analysis #MMPMID33291791
  • Ndieugnou Djangang N; Peluso L; Talamonti M; Izzi A; Gevenois PA; Garufi A; Goffard JC; Henrard S; Severgnini P; Vincent JL; Creteur J; Taccone FS
  • Microorganisms 2020[Dec]; 8 (12): ä PMID33291791show ga
  • Objectives: The aim of this study was to assess the diagnostic role of eosinophils count in COVID-19 patients. Methods: Retrospective analysis of patients admitted to our hospital with suspicion of COVID-19. Demographic, clinical and laboratory data were collected on admission. Eosinopenia was defined as eosinophils < 100 cells/mm(3). The outcomes of this study were the association between eosinophils count on admission and positive real-time reverse transcription polymerase chain reaction (rRT-PCR) test and with suggestive chest computerized tomography (CT) of COVID-19 pneumonia. Results: A total of 174 patients was studied. Of those, 54% had positive rRT-PCR for SARS-CoV-2. A chest CT-scan was performed in 145 patients; 71% showed suggestive findings of COVID-19. Eosinophils on admission had a high predictive accuracy for positive rRT-PCR and suggestive chest CT-scan (area under the receiver operating characteristic-ROC curve, 0.84 (95% CIs 0.78-0.90) and 0.84 (95% CIs 0.77-0.91), respectively). Eosinopenia and high LDH were independent predictors of positive rRT-PCR, whereas eosinopenia, high body mass index and hypertension were predictors for suggestive CT-scan findings. Conclusions: Eosinopenia on admission could predict positive rRT-PCR test or suggestive chest CT-scan for COVID-19. This laboratory finding could help to identify patients at high-risk of COVID-19 in the setting where gold standard diagnostic methods are not available.
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