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10.3390/dermatopathology7030010 http://scihub22266oqcxt.onion/10.3390/dermatopathology7030010 33291622!7768511!33291622     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dermatopathology+(Basel) 2020 ; 7 (3): 57-63 Nephropedia Template TP {{tp|p=33291622|t=2020. Type I Interferon Signature in Chilblain-Like Lesions Associated with the COVID-19 Pandemic |pdf=|usr=}}{{33291622}} gab.com Text Type I Interferon Signature in Chilblain-Like Lesions Associated with the COVID-19 Pandemic JO: Dermatopathology (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=33291622 #FOAvip Contemporarily to the new SARS-CoV-2 mediated COVID-19 pandemic, a rise in patients with acral chilblain lesions has been described. They manifest late after mild disease or asymptomatic exposure to SARS-CoV-2. Their pathogenic evolution is currently unknown. In biopsies from three patients with acral partially ulcerating chilblain lesions that occurred associated to the COVID-19 pandemic, we analysed the expression of type I interferon induced proteins and signal transduction kinases. Histology demonstrated perivascular and periadnexal lymphohistiocytic infiltrates and endothelial dominated MxA-staining, as well as pJAK1 activation. Our findings demonstrate induction of the type I IFN pathway in lesional sections of COVID-19-associated chilblain-like lesions. This may indicate a local antiviral immune activation status associated with preceding exposure to SARS-CoV-2. Twit Text FOAVip Type I Interferon Signature in Chilblain-Like Lesions Associated with the COVID-19 Pandemic ????Dermatopathology (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=33291622 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=33291622 #FOAvip English Wikipedia <ref>{{Cite pmid|33291622}}</ref> Type I Interferon Signature in Chilblain-Like Lesions Associated with the COVID-19 Pandemic #MMPMID33291622 Aschoff R; Zimmermann N; Beissert S; Gunther C Dermatopathology (Basel) 2020[Dec]; 7 (3): 57-63 PMID33291622show ga Contemporarily to the new SARS-CoV-2 mediated COVID-19 pandemic, a rise in patients with acral chilblain lesions has been described. They manifest late after mild disease or asymptomatic exposure to SARS-CoV-2. Their pathogenic evolution is currently unknown. In biopsies from three patients with acral partially ulcerating chilblain lesions that occurred associated to the COVID-19 pandemic, we analysed the expression of type I interferon induced proteins and signal transduction kinases. Histology demonstrated perivascular and periadnexal lymphohistiocytic infiltrates and endothelial dominated MxA-staining, as well as pJAK1 activation. Our findings demonstrate induction of the type I IFN pathway in lesional sections of COVID-19-associated chilblain-like lesions. This may indicate a local antiviral immune activation status associated with preceding exposure to SARS-CoV-2. äType I Interferon Signature in Chilblain-Like Lesions Associated with (epmc).pdf DeepDyve Pubget Overpricing