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Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Anticancer+Res 2020 ; 40 (12): 7119-7125 Nephropedia Template TP
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Delay in Breast Cancer Treatments During the First COVID-19 Lockdown A Multicentric Analysis of 432 Patients #MMPMID33288611
Vanni G; Tazzioli G; Pellicciaro M; Materazzo M; Paolo O; Cattadori F; Combi F; Papi S; Pistolese CA; Cotesta M; Santori F; Caspi J; Chiaravalloti A; Muscoli S; Lombardo V; Grasso A; Caggiati L; Raselli R; Palli D; Altomare V; D'Angelillo RM; Palombi L; Buonomo OC
Anticancer Res 2020[Dec]; 40 (12): 7119-7125 PMID33288611show ga
BACKGROUND/AIM: Extraordinary restrictions aimed to limit Sars-CoV-2 spreading; they imposed a total reorganization of the health-system. Oncological treatments experienced a significant slowdown. The aim of our multicentric retrospective study was to evaluate screening suspension and surgical treatment delay during COVID-19 and the impact on breast cancer presentation. PATIENTS AND METHODS: All patients who underwent breast surgery from March 11, 2020 to May 30, 2020 were evaluated and considered as the Lockdown group. These patients were compared with similar patients of the previous year, the Pre-Lockdown group. RESULTS: A total of 432 patients were evaluated; n=223 and n=209 in the Lockdown and Pre-lockdown-groups, respectively. At univariate analysis, waiting times, lymph-nodes involvement and cancer grading, showed a statistically significant difference (p<0.05). Multivariate analysis identified waiting-time on list (OR=1.07) as a statistically significant predictive factor of lymph node involvement. CONCLUSION: Although we did not observe a clinically evident difference in breast cancer presentation, we reported an increase in lymph node involvement.