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suck abstract from ncbi


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pmid33287945      Cell+Mol+Biol+(Noisy-le-grand) 2020 ; 66 (7): 143-151
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  • A comprehensive review of histopathological findings of infections induced by COVID-19 #MMPMID33287945
  • Balaky STJ; Zaki Abdullah SM; Alexander M; Maashi MS; Alkaim AF; Shahriyari S; Tabari F; Kazemi E
  • Cell Mol Biol (Noisy-le-grand) 2020[Oct]; 66 (7): 143-151 PMID33287945show ga
  • The severe acute respiratory syndrome (SARS)-Coronavirus (CoV2) virus, first identified in Wuhan, China, caused the coronavirus disease 2019 (COVID-19) which soon became a global pandemic, as labelled by the World Health Organization (WHO). The transmission method of the infection is primarily through droplets of various sizes. The SARS-CoV2 virus leads to a severe respiratory illness which in the first place causes the simulation of the acute respiratory syndrome. In order to diagnose of COVID-19 efficiently, samples with infection probability need to be examined through histopathological methods. Survival chances of the infected can remarkably increase if the virus is diagnosed timely by reverse transcription-polymerase chain reaction (RT-PCR) or computed tomography (CT) scan of the chest. One of the destructive effects of COVID-19 is the formation of ground-glass opacity (GGO) in the lungs which might be regarded to be equivalent to high-altitude pulmonary edema (HAPE). COVID-19 acts very similarly to SARS and Middle East Respiratory Syndrome (MERS) which can be inactivated by the chemical compounds of ethanol and sodium hypochlorite. Epidemiologic characteristics of COVID-19 have been indicated by numerous studies; however, there is still a lack of details of pathologic changes in the lung. The present comprehensive review is an attempt to assess and cover the current state of knowledge on COVID-19 disease based on the histopathologic studies conducted before May 2020.
  • |Biopsy[MESH]
  • |COVID-19/complications/diagnosis/*pathology[MESH]
  • |Humans[MESH]
  • |Immunohistochemistry[MESH]
  • |Kidney/pathology[MESH]
  • |Liver/pathology[MESH]
  • |Lung/*pathology[MESH]


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