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10.1016/j.breast.2020.11.015

http://scihub22266oqcxt.onion/10.1016/j.breast.2020.11.015
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suck abstract from ncbi

pmid33285400      Breast 2021 ; 55 (?): 1-6
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  • A prospective cohort study of the safety of breast cancer surgery during COVID-19 pandemic in the West of Scotland #MMPMID33285400
  • Romics L; Doughty J; Stallard S; Mansell J; Blackhall V; Lannigan A; Elgammal S; Reid J; McGuigan MC; Savioli F; Tovey S; Murphy D; Reid I; Malyon A; McIlhenny J; Wilson C
  • Breast 2021[Feb]; 55 (?): 1-6 PMID33285400show ga
  • INTRODUCTION: In order to minimise the risk of breast cancer patients for COVID-19 infection related morbidity and mortality prioritisation of care has utmost importance since the onset of the pandemic. However, COVID-19 related risk in patients undergoing breast cancer surgery has not been studied yet. We evaluated the safety of breast cancer surgery during COVID-19 pandemic in the West of Scotland region. METHODS: A prospective cohort study of patients having breast cancer surgery was carried out in a geographical region during the first eight weeks of the hospital lockdown and outcomes were compared to the regional cancer registry data of pre-COVID-19 patients of the same units (n = 1415). RESULTS: 188 operations were carried out in 179 patients. Tumour size was significantly larger in patients undergoing surgery during hospital lockdown than before (cT3-4: 16.8% vs. 7.4%; p < 0.001; pT2 - pT4: 45.5% vs. 35.6%; p = 0.002). ER negative and HER-2 positive rate was significantly higher during lockdown (ER negative: 41.3% vs. 17%, p < 0.001; HER-2 positive: 23.4% vs. 14.8%; p = 0.004). While breast conservation rate was lower during lockdown (58.6% vs. 65%; p < 0.001), level II oncoplastic conservation was significantly higher in order to reduce mastectomy rate (22.8% vs. 5.6%; p < 0.001). No immediate reconstruction was offered during lockdown. 51.2% had co-morbidity, and 7.8% developed postoperative complications in lockdown. There was no peri-operative COVID-19 infection related morbidity or mortality. CONCLUSION: breast cancer can be safely provided during COVID-19 pandemic in selected patients.
  • |Adult[MESH]
  • |Aged[MESH]
  • |Aged, 80 and over[MESH]
  • |Breast Carcinoma In Situ/pathology/surgery[MESH]
  • |Breast Neoplasms/pathology/*surgery[MESH]
  • |COVID-19/*epidemiology[MESH]
  • |Carcinoma, Ductal, Breast/pathology/surgery[MESH]
  • |Carcinoma, Intraductal, Noninfiltrating/pathology/surgery[MESH]
  • |Carcinoma, Lobular/pathology/surgery[MESH]
  • |Cohort Studies[MESH]
  • |Cross Infection/*epidemiology[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Mastectomy, Segmental/methods/statistics & numerical data[MESH]
  • |Mastectomy/*methods/statistics & numerical data[MESH]
  • |Middle Aged[MESH]
  • |Neoplasm Staging[MESH]
  • |Postoperative Complications/*epidemiology[MESH]
  • |Prospective Studies[MESH]
  • |SARS-CoV-2[MESH]
  • |Scotland/epidemiology[MESH]
  • |State Medicine[MESH]


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